Dawson Luke P, Layland Jamie
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Department of Cardiology, The Alfred Hospital, Melbourne, VIC, Australia.
Cardiol Ther. 2022 Sep;11(3):319-335. doi: 10.1007/s40119-022-00271-9. Epub 2022 Jun 22.
Advances in coronary plaque imaging over the last few decades have led to an increased interest in the identification of novel high-risk plaque features that are associated with cardiovascular events. Existing practices focus on risk stratification and lipid monitoring for primary and secondary prevention of cardiac events, which is limited by a lack of assessment and treatment of vulnerable plaque. In this review, we summarize the multitude of studies that have identified plaque, haemodynamic and patient factors associated with risk of acute coronary syndrome. Future progress in multi-modal imaging strategies and in our understanding of high-risk plaque features could expand treatment options for coronary disease and improve patient outcomes.
在过去几十年中，冠状动脉斑块成像技术的进展引发了人们对识别与心血管事件相关的新型高危斑块特征的浓厚兴趣。现有做法主要集中于心脏事件一级和二级预防的风险分层和血脂监测，但由于缺乏对易损斑块的评估和治疗而受到限制。在这篇综述中，我们总结了众多已确定与急性冠状动脉综合征风险相关的斑块、血流动力学和患者因素的研究。多模态成像策略以及我们对高危斑块特征认识方面的未来进展，可能会扩大冠心病的治疗选择并改善患者预后。
