Kuwahara M, Kambe K, Kurosu S, Kageyama S, Ioritani N, Orikasa S, Takayama K
J Urol. 1987 May;137(5):837-40. doi: 10.1016/s0022-5347(17)44268-6.
Extracorporeal stone disintegration using a chemical explosive (10 mg. lead azide) as an energy source of underwater shock waves was performed in 105 patients 11 to 72 years old who had stones in the upper urinary tract. We used a prototype disintegrator in this series. The over-all rate free of stones 3 months after treatment was 82 per cent. Shock wave therapy was performed alone in 77 patients (73 per cent), while the remainder required combined treatment with percutaneous and/or transurethral lithotripsy. The most common complications were colic pain (30 per cent) and fever (23 per cent). In 4 patients other complications, that is bacteremia, gastrointestinal bleeding, ureteral injury and subcapsular renal hematoma, were observed but they were treated conservatively with no serious adverse effects. Our study demonstrates the safe use of this method for clinical treatment.
采用化学炸药（10毫克叠氮化铅）作为水下冲击波能源进行体外碎石治疗，治疗对象为105例年龄在11至72岁的上尿路结石患者。本系列研究中我们使用了一种原型碎石机。治疗后3个月结石清除率总体为82%。77例患者（73%）仅接受了冲击波治疗，其余患者则需要联合经皮和/或经尿道碎石术治疗。最常见的并发症是绞痛（30%）和发热（23%）。4例患者出现了其他并发症，即菌血症、胃肠道出血、输尿管损伤和肾包膜下血肿，但经保守治疗后未出现严重不良反应。我们的研究表明该方法用于临床治疗是安全的。
