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高能水下冲击波对兔植入性膀胱癌的影响。

The effect of high-energy underwater shock waves on implanted urinary bladder cancer in rabbits.

作者信息

Hosi S, Orikasa S, Kuwahara M, Yoshikawa K, Ohyama C, Satoh M, Kawamura S, Nose M

机构信息

Department of Urology, Tohoku University School of Medicine, Sendai.

出版信息

Jpn J Cancer Res. 1990 Apr;81(4):317-9. doi: 10.1111/j.1349-7006.1990.tb02568.x.

Abstract

We have examined the effects of high-energy shock waves (HESW) on implanted urinary bladder cancer in rabbits. The bladder cancer was exposed to 2000 to 6000 shots of focused HESW under ultrasound guidance. Although only focal necrosis of the tumor was seen in the one-day HESW exposure (2000 shots), wider and deeper necrosis was observed in the tumors following serial HESW (4000 or 6000 shots; 2 or 3 days). These results indicate that serial HESW exposure has destructive effects on implanted bladder cancer in rabbits.

摘要

我们研究了高能冲击波(HESW)对兔植入性膀胱癌的影响。在超声引导下,使膀胱癌接受2000至6000次聚焦高能冲击波照射。虽然在单次高能冲击波照射(2000次)一天后仅见肿瘤灶性坏死,但在多次高能冲击波照射(4000次或6000次;2或3天)后的肿瘤中观察到更广泛、更深的坏死。这些结果表明,多次高能冲击波照射对兔植入性膀胱癌具有破坏作用。

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本文引用的文献

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A model of malignant urinary bladder tumor in rabbits.兔恶性膀胱肿瘤模型。
Tohoku J Exp Med. 1981 Jul;134(3):257-63. doi: 10.1620/tjem.134.257.
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Urol Int. 1988;43(5):275-81. doi: 10.1159/000281354.
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The cytocidal effect of high energy shock waves on human prostatic tumour cell lines.
Eur J Cancer Clin Oncol. 1989 Aug;25(8):1173-9. doi: 10.1016/0277-5379(89)90411-2.

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