冲击波联合吡柔比星治疗兔膀胱癌
Shock wave and THP-adriamycin for treatment of rabbit's bladder cancer.
作者信息
Hoshi S, Orikasa S, Kuwahara M, Suzuki K, Shirai S, Yoshikawa K, Nose M
机构信息
Department of Urology, Tohoku University School of Medicine, Sendai.
出版信息
Jpn J Cancer Res. 1992 Mar;83(3):248-50. doi: 10.1111/j.1349-7006.1992.tb00095.x.
Abstract
Focused high-energy shock waves (6,000 to 10,000 shots) were targeted under ultrasound guidance onto implanted urinary bladder cancer in rabbits to elucidate its effect. Although only focal necrosis of the tumor was seen following 6,000 to 10,000 shots daily for 3 days or following chemotherapy (THP-adriamycin) alone, almost total tumor necrosis was observed following a combined shock-wave therapy for one day and THP-adriamycin administration, demonstrating an additive and/or synergetic effect on rabbit urinary bladder cancer.
摘要
在超声引导下，将聚焦高能冲击波（6000至10000次冲击）作用于兔植入的膀胱癌，以阐明其效果。尽管每天进行6000至10000次冲击，持续3天或单独进行化疗（吡柔比星-阿霉素）后仅见肿瘤灶性坏死，但在冲击波治疗一天并给予吡柔比星-阿霉素后观察到几乎完全的肿瘤坏死，这表明对兔膀胱癌有相加和/或协同作用。
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