School of Medicine, University of California Irvine, Irvine, USA.
Department of Radiological Sciences, University of California Irvine, Orange, USA.
Br J Radiol. 2022 Sep 1;95(1138):20211360. doi: 10.1259/bjr.20211360. Epub 2022 Jul 6.
Interventional oncology is a rapidly emerging field in the treatment of cancer. Minimally invasive techniques such as transarterial embolization with chemotherapeutic and radioactive agents are established therapies and are found in multiple guidelines for the management of primary and metastatic liver lesions. Percutaneous ablation is also an alternative to surgery for small liver, renal, and pancreatic tumors. Recent research in the niche of interventional oncology has focused on improving outcomes of established techniques in addition to the development of novel therapies. In this review, we address the recent and current advancements in devices, technologies, and techniques of chemoembolization and ablation: thermal ablation, histotripsy, high-intensity focused ultrasound, embolization strategies, liquid embolic agents, and local immunotherapy/antiviral therapies.
介入肿瘤学是癌症治疗中一个迅速发展的领域。经动脉栓塞术联合化疗药物和放射性药物等微创技术已成为既定疗法，并且在原发性和转移性肝脏病变的多种管理指南中都有涉及。对于小的肝、肾和胰腺肿瘤，经皮消融也是一种替代手术的方法。介入肿瘤学领域的最新研究除了开发新疗法外，还侧重于提高既定技术的治疗效果。在这篇综述中，我们讨论了化学栓塞和消融的设备、技术和技术的最新和当前进展：热消融、组织爆破、高强度聚焦超声、栓塞策略、液体栓塞剂以及局部免疫疗法/抗病毒疗法。
