The Future of Transplantation.
作者信息
Platt Jeffrey L, Cascalho Marilia
机构信息
From the Department of Surgery and the Department of Microbiology and Immunology, University of Michigan, Ann Arbor.
出版信息
N Engl J Med. 2022 Jul 7;387(1):77-78. doi: 10.1056/NEJMe2207105. Epub 2022 Jun 22.
Abstract
摘要
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Genetically Modified Porcine-to-Human Cardiac Xenotransplantation.基因编辑猪-人心脏异种移植。
N Engl J Med. 2022 Jul 7;387(1):35-44. doi: 10.1056/NEJMoa2201422. Epub 2022 Jun 22.
3
Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months.猪心异种移植物的渐进式遗传修饰将存活时间延长至 9 个月。
Xenotransplantation. 2022 May;29(3):e12744. doi: 10.1111/xen.12744. Epub 2022 Mar 31.
4
The growth of xenotransplanted hearts can be reduced with growth hormone receptor knockout pig donors.异种移植心脏的生长可以通过生长激素受体敲除猪供体来减少。
J Thorac Cardiovasc Surg. 2023 Feb;165(2):e69-e81. doi: 10.1016/j.jtcvs.2021.07.051. Epub 2021 Sep 4.
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Pig-to-non-human primate heart transplantation: The final step toward clinical xenotransplantation?猪到非灵长类动物心脏移植：临床异种移植的最后一步？
J Heart Lung Transplant. 2020 Aug;39(8):751-757. doi: 10.1016/j.healun.2020.05.004. Epub 2020 May 15.
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Xenotransplantation: Progress Along Paths Uncertain from Models to Application.异种移植：从模型到应用，在充满不确定性的道路上取得的进展。
ILAR J. 2018 Dec 31;59(3):286-308. doi: 10.1093/ilar/ily015.
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Solid-organ transplantation in older adults: current status and future research.老年人实体器官移植：现状与未来研究。
Am J Transplant. 2012 Oct;12(10):2608-22. doi: 10.1111/j.1600-6143.2012.04245.x. Epub 2012 Sep 7.
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Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine.小鼠心脏和小肠中随年龄积累的体细胞突变具有不同的光谱。
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Transplantation of discordant xenografts: a review of progress.异种移植：进展综述
Immunol Today. 1990 Dec;11(12):450-6; discussion 456-7. doi: 10.1016/0167-5699(90)90174-8.
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