Damughatla Anirudh R, Surapaneni Sarvani, Wadehra Anshu, Kabashneh Sohaip, Shanah Layla
Internal Medicine, Wayne State University Detroit Medical Center, Detroit, USA.
Cureus. 2022 May 18;14(5):e25116. doi: 10.7759/cureus.25116. eCollection 2022 May.
It is well known that most medications have side effects, and many of them have gone through years of testing with thousands of test subjects before entering the market. However, as physicians it is important to assess how patients react to the initiation of new medications not only looking for known side effects but also rare ones. Our case highlights a rare presentation of metformin-induced pancreatitis in the setting of normal renal function and appropriate dosing. We are hoping our case will create more awareness and inspire future research in exploring the pathophysiology and causes of metformin-induced pancreatitis. Moreover, we aim to make healthcare professionals mindful so that they may recognize acute pancreatitis as a side effect of metformin even in a healthy patient.
众所周知，大多数药物都有副作用，其中许多药物在进入市场之前已经经过了针对数千名受试者的多年测试。然而，作为医生，重要的是评估患者对新药起始治疗的反应，不仅要寻找已知的副作用，还要寻找罕见的副作用。我们的病例突出了在肾功能正常且剂量合适的情况下，二甲双胍诱发胰腺炎的罕见表现。我们希望我们的病例能提高更多认识，并激发未来对探索二甲双胍诱发胰腺炎的病理生理学和病因的研究。此外，我们旨在让医疗保健专业人员提高警惕，以便他们即使在健康患者中也能认识到急性胰腺炎是二甲双胍的一种副作用。
