Barlas Aisha, Ramachandran Lintu
Department of Internal Medicine, Javon Bea Hospital, Rockford, USA.
Maedica (Bucur). 2022 Mar;17(1):234-236. doi: 10.26574/maedica.2022.17.1.234.
Sarcoidosis is a systemic granulomatous disease involving multiple organs with predominantly pulmonary manifestations. Severe thrombocytopenia is a relatively rare hematologic manifestation of sarcoidosis. Immune thrombocytopenia is usually characterized by excessive antibody production leading to platelet destruction. There are a few reported cases of immune thrombocytopenic purpura secondary to sarcoidosis, but the pathophysiologic mechanism remains unknown. We report the case of a 65-year-old woman who presented severe thrombocytopenia and was found to have immune thrombocytopenic purpura secondary to sarcoidosis.
结节病是一种累及多个器官的全身性肉芽肿性疾病,主要表现为肺部症状。严重血小板减少是结节病相对罕见的血液学表现。免疫性血小板减少通常表现为抗体过度产生导致血小板破坏。有少数关于结节病继发免疫性血小板减少性紫癜的病例报道,但病理生理机制仍不清楚。我们报告一例65岁女性患者,该患者出现严重血小板减少,被发现患有结节病继发免疫性血小板减少性紫癜。