Fordice J, Katras T, Jackson R E, Cagle P T, Jackson D, Zaleski H, Asimacopoulos P J
Baylor College of Medicine, Houston, Tex.
South Med J. 1992 Jul;85(7):775-8. doi: 10.1097/00007611-199207000-00028.
We have presented a case of massive splenomegaly. Our patient was initially thought to have lymphoma, but at operation she was found to have sarcoidosis with splenic involvement. At 2250 g, the spleen was one of the largest recorded in the literature on sarcoidosis. Although the spleen is frequently involved in sarcoidosis, a review of 6074 cases showed that the incidence of actual splenomegaly is only 10%. In 628 of these cases the authors described various degrees of splenomegaly, but the incidence of massive splenomegaly was only 3%. We conclude that sarcoidosis must be considered in the differential diagnosis of splenomegaly.
我们报告了一例巨脾症病例。我们的患者最初被认为患有淋巴瘤，但手术时发现她患的是累及脾脏的结节病。脾脏重达2250克，是结节病文献记载中最大的脾脏之一。尽管脾脏在结节病中常被累及，但对6074例病例的回顾显示，实际脾肿大的发生率仅为10%。在其中628例病例中，作者描述了不同程度的脾肿大，但巨脾症的发生率仅为3%。我们得出结论，在脾肿大的鉴别诊断中必须考虑结节病。
