Fly Laboratory #210, Anusandhan Kendra-II, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur 613401, Tamil Nadu, India.
Biol Open. 2022 Jul 15;11(7). doi: 10.1242/bio.059273. Epub 2022 Jul 25.
Rapid technology development, exposure to gadgets, and artificial lights (with different monochromes) have disturbed our lifestyle and the circadian clock, which otherwise confers better regulation of behavioral patterns and sleep:wake cycles in most organisms including Drosophila melanogaster. We assay the effect of LD12:12 h (light:dark) monochromatic lights (violet, blue, green, yellow, orange, and red) on the lifespan, activity, and sleep of the D. melanogaster. We observe a shortened lifespan under 12 h of violet, blue, green, and yellow lights, while significantly reduced activity levels under the light phase of blue and green light as compared to their dark phase is observed. Significant increase in the evening anticipation index of flies under blue and green light alongside increased and decreased sleep depth during the day and night respectively suggests the light avoidance, while there is no effect of colored light on the waking time, daily active time, and sleep time. Thus, our study shows short and long-term exposure to certain colored lights in terms of reduced lifespan and locomotor activity, which cause qualitative as well as quantitative changes in the sleep of flies; probably as a sign of aversion towards a specific light. This article has an associated First Person interview with the first author of the paper.
快速的技术发展、接触小工具和人工灯光（具有不同的单色）扰乱了我们的生活方式和生物钟，否则生物钟可以更好地调节大多数生物体（包括黑腹果蝇）的行为模式和睡眠-觉醒周期。我们检测了 LD12:12h（光照：黑暗）单色光（紫光、蓝光、绿光、黄光、橙光和红光）对黑腹果蝇寿命、活动和睡眠的影响。我们观察到在 12 小时的紫光、蓝光、绿光和黄光下，寿命缩短，而与黑暗期相比，蓝绿光光相下的活动水平显著降低。与白天相比，蓝绿光下苍蝇傍晚预期指数显著增加，而白天和黑夜的睡眠时间分别增加和减少，这表明苍蝇对光有回避作用，而有色光对清醒时间、每日活动时间和睡眠时间没有影响。因此，我们的研究表明，短期和长期暴露于某些有色光会降低果蝇的寿命和运动活性，从而导致睡眠的定性和定量变化；这可能是对特定光的厌恶的迹象。本文有该论文第一作者的相关第一人称采访。
