College of Life Information Science & Instrument Engineering, Hangzhou Dianzi University, Hangzhou 310018, China..
College of Life Information Science & Instrument Engineering, Hangzhou Dianzi University, Hangzhou 310018, China.
Exp Gerontol. 2021 May;147:111268. doi: 10.1016/j.exger.2021.111268. Epub 2021 Feb 1.
The role of visible light on longevity is incompletely understood. Here we show the effect of visible light in Drosophila melanogaster is wavelength specific. Life span was significantly extended by green light, whereas blue light reduced longevity dramatically, and minor impact was observed with red light. While oxidative stress, heat stress, or caloric restriction does not contribute to the beneficial effect of green light, our study found that the life span extension effect of green light might be mediated by microbiota or photosensitive micronutrients in food medium. In conclusion, we report that green light can extend longevity and present the potential of light as a noninvasive therapy for aging-related diseases.
可见光对长寿的作用尚未完全阐明。在这里，我们发现可见光对果蝇的影响具有波长特异性。绿光显著延长了寿命，而蓝光则大大缩短了寿命，红光的影响较小。虽然氧化应激、热应激或热量限制都不会对绿光的有益效果产生影响，但我们的研究发现，绿光延长寿命的效果可能是由微生物群或食物中的光敏微量营养素介导的。总之，我们报告了绿光可以延长寿命，并提出了将光作为一种非侵入性治疗与衰老相关疾病的潜力。
