Chichkanov G G, Tsorin I B
Farmakol Toksikol. 1986 Jan-Feb;49(1):52-6.
It was shown in experiments on anesthetized cats with modelled acute coronary insufficiency that sodium hydroxybutyrate (200 mg/kg) and in a lesser degree piracetam (400 mg/kg) improve the functional state of the acute myocardial ischemic focus, reduce the rate of growth of creatinephosphokinase activity in coronary sinus blood, increase the retrograde bloodflow to the ischemized zone. Glyo-6 (100 mg/kg) has practically no effect on the investigated indicators.
在对模拟急性冠状动脉供血不足的麻醉猫进行的实验中发现,羟基丁酸钠(200毫克/千克)以及程度稍轻的吡拉西坦(400毫克/千克)可改善急性心肌缺血灶的功能状态,降低冠状窦血中肌酸磷酸激酶活性的增长速率,增加流向缺血区的逆行血流量。Glyo-6(100毫克/千克)对所研究指标实际上没有影响。