Marin Davide, Marchesan Silvia
Chemical and Pharmaceutical Sciences Department, University of Trieste, 34127 Trieste, Italy.
Biomedicines. 2022 Jun 4;10(6):1320. doi: 10.3390/biomedicines10061320.
Carbon nanomaterials have attracted great interest for their unique physico-chemical properties for various applications, including medicine and, in particular, drug delivery, to solve the most challenging unmet clinical needs. Graphitization is a process that has become very popular for their production or modification. However, traditional conditions are energy-demanding; thus, recent efforts have been devoted to the development of greener routes that require lower temperatures or that use waste or byproducts as a carbon source in order to be more sustainable. In this concise review, we analyze the progress made in the last five years in this area, as well as in their development as drug delivery agents, focusing on active targeting, and conclude with a perspective on the future of the field.
碳纳米材料因其独特的物理化学性质在包括医学在内的各种应用中引起了极大的兴趣,特别是在药物递送方面,以解决最具挑战性的未满足临床需求。石墨化是一种在其生产或改性过程中非常流行的工艺。然而,传统条件需要大量能源;因此,最近人们致力于开发更环保的路线,这些路线需要更低的温度,或者使用废物或副产品作为碳源,以实现更高的可持续性。在这篇简要综述中,我们分析了该领域在过去五年中取得的进展,以及它们作为药物递送剂的发展情况,重点是主动靶向,并对该领域的未来进行了展望。