Department of Chemistry, Faculty of Science, University of Qom, Qom, Iran.
Department of Physics, Bu-Ali Sina University, Hamedan, Iran.
J Drug Target. 2021 Aug;29(7):716-741. doi: 10.1080/1061186X.2021.1886301. Epub 2021 Feb 18.
Carbon-based nanomaterials are becoming attractive materials due to their unique structural dimensions and promising mechanical, electrical, thermal, optical and chemical characteristics. Carbon nanotubes, graphene, graphene oxide, carbon and graphene quantum dots have numerous applications in diverse areas, including biosensing, drug/gene delivery, tissue engineering, imaging, regenerative medicine, diagnosis, and cancer therapy. Cancer remains one of the major health problems all over the world, and several therapeutic approaches are focussed on designing targeted anticancer drug delivery nanosystems by applying benign and less hazardous resources with high biocompatibility, ease of functionalization, remarkable targeted therapy issues, and low adverse effects. This review highlights the recent development on these carbon based-nanomaterials in the field of targeted cancer therapy and discusses their possible and promising diagnostic and therapeutic applications for the treatment of cancers.
由于其独特的结构尺寸和有前途的机械、电气、热、光和化学特性，碳基纳米材料正成为一种极具吸引力的材料。碳纳米管、石墨烯、氧化石墨烯、碳和石墨烯量子点在生物传感、药物/基因传递、组织工程、成像、再生医学、诊断和癌症治疗等多个领域有广泛的应用。癌症仍然是全世界主要的健康问题之一，许多治疗方法集中于通过应用良性和危害较小的资源来设计靶向抗癌药物输送纳米系统，这些资源具有高生物相容性、易于功能化、显著的靶向治疗问题和低副作用。本文重点介绍了这些碳基纳米材料在靶向癌症治疗领域的最新进展，并讨论了它们在癌症治疗方面的潜在和有前途的诊断和治疗应用。
