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重度抑郁障碍和双相情感障碍中自我报告的童年期虐待情况无性别差异:一项回顾性研究

No Sex Differences in Self-Reported Childhood Maltreatment in Major Depressive and Bipolar Disorders: A Retrospective Study.

作者信息

Caldirola Daniela, Torti Tatiana, Cuniberti Francesco, Daccò Silvia, Alciati Alessandra, Schruers Koen, Martinotti Giovanni, De Berardis Domenico, Perna Giampaolo

机构信息

Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Pieve Emanuele, Italy.

Department of Clinical Neurosciences, Villa San Benedetto Menni Hospital, Hermanas Hospitalarias, Via Roma 16, 22032 Albese con Cassano, Italy.

出版信息

Brain Sci. 2022 Jun 19;12(6):804. doi: 10.3390/brainsci12060804.

Abstract

BACKGROUND

We investigated, for the first time, whether there are any sex differences in retrospective self-reported childhood maltreatment (CM) in Italian adult patients with major depressive disorder (MDD) or bipolar disorder (BD). Furthermore, the potential impacts of patients' age on the CM self-report were investigated.

METHODS

This retrospective study used the data documented in the electronic medical records of patients who were hospitalized for a 4-week psychiatric rehabilitation program. CM was assessed using the 28-item Childhood Trauma Questionnaire (CTQ), which evaluates emotional, physical, and sexual abuse, as well as emotional and physical neglect. The linear and logistic regression models were used (α = 0.01).

RESULTS

Three hundred thirty-five patients with MDD (255 women and 80 men) and 168 with BD (97 women and 71 men) were included. In both samples, considerable CM rates were identified, but no statistically significant sex differences were detected in the variety of CTQ-based CM aspects. There was a significant association, with no sex differences, between increasing patients' age and a decreasing burden of CM.

CONCLUSION

Both women and men with MDD or BD experienced a similar and considerable CM burden. Our findings support routine CM assessment in psychiatric clinical practice.

摘要

背景

我们首次调查了意大利成年重度抑郁症(MDD)或双相情感障碍(BD)患者在回顾性自我报告童年虐待(CM)方面是否存在性别差异。此外,还研究了患者年龄对CM自我报告的潜在影响。

方法

这项回顾性研究使用了因为期4周的精神科康复计划而住院的患者电子病历中记录的数据。使用28项儿童创伤问卷(CTQ)评估CM,该问卷评估情感、身体和性虐待以及情感和身体忽视。使用线性和逻辑回归模型(α = 0.01)。

结果

纳入了335例MDD患者(255名女性和80名男性)和168例BD患者(97名女性和71名男性)。在两个样本中,均发现了相当高的CM发生率,但在基于CTQ的CM各方面未检测到统计学上显著的性别差异。患者年龄增加与CM负担减轻之间存在显著关联,且无性别差异。

结论

患有MDD或BD的女性和男性都经历了相似且相当大的CM负担。我们的研究结果支持在精神科临床实践中进行常规CM评估。

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