Tam A, Herrington M B, Kapoor V, Newman E B
J Bacteriol. 1978 Sep;135(3):1154-5. doi: 10.1128/jb.135.3.1154-1155.1978.
A mutation at a single locus, wyb, results in several phenotypic changes in Escherichia coli K-12. The Wyb- phenotype includes: (i) an increase in L-serine deaminase activity, together with a loss of inducibility by L-leucine; (ii) an absence of L-leucyl-, L-phenylalanyl-tRNA protein transferase activity; (iii) inducibility of proline oxidase by proline; and (iv) a loss of ability to use maltose as a carbon and energy source.
单个基因座wyb处的突变会导致大肠杆菌K - 12出现多种表型变化。Wyb-表型包括:(i)L - 丝氨酸脱氨酶活性增加,同时丧失L - 亮氨酸诱导性;(ii)缺乏L - 亮氨酰 - 、L - 苯丙氨酰 - tRNA蛋白质转移酶活性;(iii)脯氨酸可诱导脯氨酸氧化酶;(iv)丧失利用麦芽糖作为碳源和能源的能力。