苏氨酸脱氢酶在大肠杆菌苏氨酸降解中的作用。
Role of threonine dehydrogenase in Escherichia coli threonine degradation.
作者信息
Potter R, Kapoor V, Newman E B
出版信息
J Bacteriol. 1977 Nov;132(2):385-91. doi: 10.1128/jb.132.2.385-391.1977.
Abstract
Threonine was used as nitrogen source by Escherichia coli K-12 through a pathway beginning with the enzyme threonine dehydrogenase. The 2-amino-3-ketobutyrate formed was converted to glycine, and the glycine was converted to serine, which acted as the actual nitrogen donor. The enzyme formed under anaerobic conditions and known as threonine deaminase (biodegradative) is less widespread than threonine dehydrogenase and may be involved in energy metabolism rather than in threonine degradation per se.
摘要
大肠杆菌K-12通过一条始于苏氨酸脱氢酶的途径将苏氨酸用作氮源。生成的2-氨基-3-酮丁酸被转化为甘氨酸，甘氨酸又被转化为丝氨酸，丝氨酸作为实际的氮供体。在厌氧条件下形成的、被称为苏氨酸脱氨酶（生物降解型）的酶不如苏氨酸脱氢酶分布广泛，它可能参与能量代谢而非苏氨酸本身的降解。
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