• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

韩国一项随机对照试验研究:方步走锻炼计划对老年人跌倒相关健康和 BDNF 水平的影响。

Square-Stepping Exercise Program Effects on Fall-Related Fitness and BDNF Levels in Older Adults in Korea: A Randomized Controlled Trial.

机构信息

Department of Antiaging Healthcare, Changwon National University, Changwon 51140, Korea.

Department of Marine Leisure and Tourism, Youngsan University, Busan 50510, Korea.

出版信息

Int J Environ Res Public Health. 2022 Jun 8;19(12):7033. doi: 10.3390/ijerph19127033.

DOI:10.3390/ijerph19127033
PMID:35742280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9222997/
Abstract

The risk of dementia increases with age. To mitigate this risk, we examined the effect of a square-stepping exercise (SSE) program on fall-related fitness and brain-derived neurotrophic factor (BDNF) levels. Twenty older adults in Korea were randomly assigned to either the experimental or control group (each group n = 10). Participants performed SSE for 70 min per session, twice a week, for 12 weeks with a certified instructor. The average age of the participants was 74.80 ± 6.763 years in the exercise group and 72.50 ± 6.519 years in the control group. The experiment group showed significant improvement (p < 0.01) in the lower muscle strength post-intervention. The paired t-test revealed a significant improvement (p < 0.01) in the experimental group and a significant difference in the interaction effect (p < 0.01) in the BDNF levels. There was a significant improvement (p < 0.05) in the BDNF levels in the experimental group and a significant decrease (p < 0.05) in the control group. The SSE program had a positive effect on fall-related fitness and BDNF levels.

摘要

痴呆症的风险随着年龄的增长而增加。为了降低这种风险,我们研究了方形踏步运动(SSE)对与跌倒相关的健康和脑源性神经营养因子(BDNF)水平的影响。韩国的 20 名老年人被随机分配到实验组或对照组(每组 n = 10)。参与者在有认证教练的指导下,每周进行两次,每次 70 分钟的 SSE,共 12 周。实验组参与者的平均年龄为 74.80 ± 6.763 岁,对照组为 72.50 ± 6.519 岁。实验后,实验组下肢肌肉力量明显提高(p < 0.01)。配对 t 检验显示实验组有显著改善(p < 0.01),交互效应有显著差异(p < 0.01),BDNF 水平也有显著改善。实验组 BDNF 水平显著提高(p < 0.05),对照组显著降低(p < 0.05)。SSE 方案对与跌倒相关的健康和 BDNF 水平有积极影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/9222997/80354a631cab/ijerph-19-07033-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/9222997/e532bfa1c85f/ijerph-19-07033-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/9222997/80354a631cab/ijerph-19-07033-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/9222997/e532bfa1c85f/ijerph-19-07033-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d5/9222997/80354a631cab/ijerph-19-07033-g002.jpg

相似文献

1
Square-Stepping Exercise Program Effects on Fall-Related Fitness and BDNF Levels in Older Adults in Korea: A Randomized Controlled Trial.韩国一项随机对照试验研究:方步走锻炼计划对老年人跌倒相关健康和 BDNF 水平的影响。
Int J Environ Res Public Health. 2022 Jun 8;19(12):7033. doi: 10.3390/ijerph19127033.
2
The effects of multimodal exercise on cognitive and physical functioning and brain-derived neurotrophic factor in older women: a randomised controlled trial.多模式运动对老年女性认知和身体功能以及脑源性神经营养因子的影响:一项随机对照试验。
Age Ageing. 2014 Sep;43(5):623-9. doi: 10.1093/ageing/afu010. Epub 2014 Feb 18.
3
Aerobic-synergized exercises may improve fall-related physical fitness in older adults.有氧协同运动可能会改善老年人与跌倒相关的身体素质。
J Sports Med Phys Fitness. 2017 May;57(5):660-669. doi: 10.23736/S0022-4707.16.05728-5.
4
Increase of circulating BDNF levels and its relation to improvement of physical fitness following 12 weeks of combined exercise in chronic patients with schizophrenia: a pilot study.12 周联合运动对慢性精神分裂症患者循环 BDNF 水平的影响及其与身体适应性改善的关系:一项初步研究。
Psychiatry Res. 2014 Dec 30;220(3):792-6. doi: 10.1016/j.psychres.2014.09.020.
5
Square-stepping exercise and fall risk factors in older adults: a single-blind, randomized controlled trial.老年人方步锻炼与跌倒风险因素:一项单盲随机对照试验
J Gerontol A Biol Sci Med Sci. 2008 Jan;63(1):76-82. doi: 10.1093/gerona/63.1.76.
6
Square-stepping exercise versus strength and balance training for fall risk factors.方形步训练与力量及平衡训练对跌倒风险因素的影响
Aging Clin Exp Res. 2008 Feb;20(1):19-24. doi: 10.1007/BF03324743.
7
A best practice fall prevention exercise program to improve balance, strength / power, and psychosocial health in older adults: study protocol for a randomized controlled trial.一项最佳实践的跌倒预防运动方案,旨在改善老年人的平衡、力量/功率和心理社会健康:一项随机对照试验的研究方案。
BMC Geriatr. 2013 Oct 9;13:105. doi: 10.1186/1471-2318-13-105.
8
Effects of 6-Month Square Stepping Exercise Intervention on Physical and Cognitive Competence, Regucalcin, and Body Composition in Older People: Study Protocol for a Randomised Control Trial.6 个月方步走锻炼干预对老年人身体和认知能力、Regucalcin 及身体成分的影响:一项随机对照试验研究方案。
Int J Environ Res Public Health. 2022 Mar 6;19(5):3086. doi: 10.3390/ijerph19053086.
9
Aotake: a modified stepping exercise as a useful means of improving lower-extremity functional fitness in older adults.Aotake:一种改良的踏步运动,是提高老年人下肢功能健康的有用方法。
Geriatr Gerontol Int. 2010 Jul;10(3):244-50. doi: 10.1111/j.1447-0594.2010.00613.x. Epub 2010 Mar 23.
10
Multitarget stepping program in combination with a standardized multicomponent exercise program can prevent falls in community-dwelling older adults: a randomized, controlled trial.多目标踏步程序联合标准化多组分运动程序可预防社区居住的老年人跌倒:一项随机对照试验。
J Am Geriatr Soc. 2013 Oct;61(10):1669-75. doi: 10.1111/jgs.12453. Epub 2013 Sep 3.

引用本文的文献

1
Exercise interventions and serum IGF-1 levels in older adults with frailty and/or sarcopenia: a systematic review and meta analysis.衰弱和/或肌肉减少症老年人的运动干预与血清胰岛素样生长因子-1水平:一项系统评价和荟萃分析
Front Public Health. 2025 Aug 21;13:1660694. doi: 10.3389/fpubh.2025.1660694. eCollection 2025.
2
Effects of Square Stepping Exercise on Physical, Cognitive and Psychosocial Fitness in People with Parkinson's Disease.方形踏步运动对帕金森病患者身体、认知和心理社会健康的影响。
Psychiatr Q. 2025 Aug 13. doi: 10.1007/s11126-025-10197-9.
3
Mechanisms of interventions targeting modifiable factors for dementia risk reduction.

本文引用的文献

1
Acute effects of Square Stepping Exercise on cognitive and social functions in sedentary young adults: a home-based online trial.方形踏步运动对久坐不动的年轻成年人认知和社交功能的急性影响:一项基于家庭的在线试验。
BMC Sports Sci Med Rehabil. 2021 Aug 2;13(1):82. doi: 10.1186/s13102-021-00309-w.
2
Investigating the Relationship Between IGF-I, IGF-II, and IGFBP-3 Concentrations and Later-Life Cognition and Brain Volume.研究 IGF-I、IGF-II 和 IGFBP-3 浓度与晚年认知和大脑体积的关系。
J Clin Endocrinol Metab. 2021 May 13;106(6):1617-1629. doi: 10.1210/clinem/dgab121.
3
Acute effects of strength and endurance exercise on serum BDNF and IGF-1 levels in older men.
针对可改变因素降低痴呆风险的干预机制。
Mol Neurodegener. 2025 Jun 23;20(1):75. doi: 10.1186/s13024-025-00845-w.
4
Effects of Twelve Weeks of Square Stepping Exercises on Physical and Cognitive Function and Plasma Content of SMP30: A Randomised Control Trial.十二周方形踏步运动对身体和认知功能及血浆SMP30含量的影响:一项随机对照试验
Geriatrics (Basel). 2025 Feb 7;10(1):22. doi: 10.3390/geriatrics10010022.
5
Impacts of Square Stepping Exercise on Physical-Cognitive Function, Biomarkers, Body Composition and Mental Health in Healthy Senior Aged 60 and Above: A Systematic Review.方形踏步运动对60岁及以上健康老年人身体认知功能、生物标志物、身体成分和心理健康的影响:一项系统综述
Healthcare (Basel). 2024 Nov 21;12(23):2325. doi: 10.3390/healthcare12232325.
6
Stepping towards health: a scoping review of square-stepping exercise protocols and outcomes in older adults.迈向健康:老年人方步走锻炼方案和效果的范围综述。
BMC Geriatr. 2024 Jul 10;24(1):590. doi: 10.1186/s12877-024-05187-8.
7
New insight of square stepping exercise in immune fine-tuning for anticipating emerging pandemics.方形踏步运动在免疫微调以应对新出现的大流行方面的新见解。
Anim Cells Syst (Seoul). 2024 May 7;28(1):251-260. doi: 10.1080/19768354.2024.2350157. eCollection 2024.
老年人力量和耐力训练对血清 BDNF 和 IGF-1 水平的急性影响。
BMC Geriatr. 2021 Jan 13;21(1):50. doi: 10.1186/s12877-020-01937-6.
4
The Effects of Physical Exercise on Balance and Prevention of Falls in Older People: A Systematic Review and Meta-Analysis.体育锻炼对老年人平衡能力及跌倒预防的影响:一项系统评价与Meta分析
J Clin Med. 2020 Aug 11;9(8):2595. doi: 10.3390/jcm9082595.
5
The Effects of Exercise Training on the Brain-Derived Neurotrophic Factor (BDNF) in the Patients with Type 2 Diabetes: A Systematic Review of the Randomized Controlled Trials.运动训练对2型糖尿病患者脑源性神经营养因子(BDNF)的影响:随机对照试验的系统评价
J Diabetes Metab Disord. 2020 May 6;19(1):633-643. doi: 10.1007/s40200-020-00529-w. eCollection 2020 Jun.
6
The Val66Met Polymorphism Modulates Resilience of Neurological Functioning to Brain Ageing and Dementia: A Narrative Review.缬氨酸66蛋氨酸多态性调节神经功能对脑衰老和痴呆的恢复力:一项叙述性综述。
Brain Sci. 2020 Mar 25;10(4):195. doi: 10.3390/brainsci10040195.
7
Influence of Acute and Chronic High-Intensity Intermittent Aerobic Plus Strength Exercise on BDNF, Lipid and Autonomic Parameters.急性和慢性高强度间歇有氧运动加力量训练对 BDNF、血脂和自主神经参数的影响。
J Sports Sci Med. 2019 Jun 1;18(2):359-368. eCollection 2019 Jun.
8
Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model.联合成年神经发生和 BDNF 模拟运动对阿尔茨海默病小鼠模型认知的影响。
Science. 2018 Sep 7;361(6406). doi: 10.1126/science.aan8821.
9
Fatal falls in the elderly and the presence of proximal femur fractures.老年人的致命跌倒与股骨近端骨折的存在。
Int J Legal Med. 2018 Nov;132(6):1699-1712. doi: 10.1007/s00414-018-1876-7. Epub 2018 Jun 7.
10
Deaths from Falls Among Persons Aged ≥65 Years - United States, 2007-2016.2007-2016 年美国≥65 岁人群因跌倒导致的死亡人数。
MMWR Morb Mortal Wkly Rep. 2018 May 11;67(18):509-514. doi: 10.15585/mmwr.mm6718a1.