Ogawa Masato, Okamura Masatsugu, Yagi Takuma, Maekawa Kenichiro, Amakasu Kota, Inoue Tatsuro, Satomi-Kobayashi Seimi, Katayama Megumi, Muraki Yumi, Akashi Masaya
Division of Rehabilitation Medicine, Kobe University Graduate School of Medicine Kobe Japan.
Department of Rehabilitation, Osaka Health Science University Osaka Japan.
Circ Rep. 2025 Mar 1;7(4):223-230. doi: 10.1253/circrep.CR-24-0187. eCollection 2025 Apr 10.
Oral frailty, which encompasses decline in oral health and function with aging, has broader health implications. However, its specific role in individuals with cardiovascular disease (CVD) remains poorly understood. In this scoping review we investigated the prevalence, assessment tools, and potential intervention strategies for oral frailty in patients with CVD. We used the Population, Concept, and Context framework as follows: Population: Patients with CVD; Concept: Existing literature on oral frailty in the context of CVD; Context: Not restricted. Extracted data were synthesized qualitatively. From an initial pool of 3,199 studies, 70 were included in the final analysis, with a cumulative sample size of 891,450 individuals. Among the assessment tools for oral frailty, the number of teeth was the most commonly used measure in 39 studies, followed by the Decayed, Missing, Filled Index. Of the studies, 5 studies indicated that coronary artery disease and diabetes are risk factors for oral frailty, and 8 identified poor oral health as a predictor of cardiac events. However, no study clearly defined oral frailty in the context of CVD. Additionally, only 2 studies explored the relationship between oral health and physical frailty. This results of this review underscore the lack of a standardized definition for oral frailty in CVD. Although associations between oral health and prognosis were observed, further research is needed to clarify the definitions and explore causal relationships.
口腔衰弱是指随着年龄增长口腔健康和功能出现衰退,它对整体健康有着更广泛的影响。然而,其在心血管疾病(CVD)患者中的具体作用仍知之甚少。在这项范围综述中,我们调查了CVD患者口腔衰弱的患病率、评估工具和潜在干预策略。我们采用了人群、概念和背景框架,具体如下:人群:CVD患者;概念:CVD背景下关于口腔衰弱的现有文献;背景:不设限制。提取的数据进行了定性综合分析。从最初的3199项研究中,最终纳入分析70项,累计样本量为891450人。在口腔衰弱的评估工具中,牙齿数量是39项研究中最常用的指标,其次是龋失补指数。在这些研究中,5项研究表明冠状动脉疾病和糖尿病是口腔衰弱的危险因素,8项研究确定口腔健康状况差是心脏事件的预测因素。然而,没有研究在CVD背景下明确界定口腔衰弱。此外,只有2项研究探讨了口腔健康与身体衰弱之间的关系。本综述结果强调了在CVD中缺乏口腔衰弱的标准化定义。尽管观察到口腔健康与预后之间的关联,但仍需要进一步研究来明确定义并探索因果关系。