Falcão Lucas de Souza, Coelho Deborah Bento, Veggi Priscilla Carvalho, Campelo Pedro Henrique, Albuquerque Patrícia Melchionna, de Moraes Mariana Agostini
Department of Chemical Engineering, Federal University of Sao Paulo, UNIFESP, Diadema 09913-030, SP, Brazil.
Department of Food Technology, Federal University of Viçosa, Viçosa 36570-900, MG, Brazil.
Polymers (Basel). 2022 Jun 10;14(12):2361. doi: 10.3390/polym14122361.
Due to its abundance in nature and low cost, starch is one of the most relevant raw materials for replacing synthetic polymers in a number of applications. It is generally regarded as non-toxic, biocompatible, and biodegradable and, therefore, a safe option for biomedical, food, and packaging applications. In this review, we focused on studies that report the use of starch as a matrix for stabilization, incorporation, or release of bioactive compounds, and explore a wide range of applications of starch-based materials. One of the key application areas for bioactive compounds incorporated in starch matrices is the pharmaceutical industry, especially in orally disintegrating films. The packaging industry has also shown great interest in using starch films, especially those with antioxidant activity. Regarding food technology, starch can be used as a stabilizer in nanoemulsions, thus allowing the incorporation of bioactive compounds in a variety of food types. Starch also presents potential in the cosmetic industry as a delivery system. However, there are still several types of industry that could benefit from the incorporation of starch matrices with bioactive compounds, which are described in this review. In addition, the use of microbial bioactive compounds in starch matrices represents an almost unexplored field still to be investigated.
由于淀粉在自然界中储量丰富且成本低廉，它是许多应用中替代合成聚合物的最重要原材料之一。淀粉通常被认为无毒、具有生物相容性且可生物降解，因此是生物医学、食品和包装应用的安全选择。在本综述中，我们重点关注了那些报道将淀粉用作生物活性化合物的稳定化、包埋或释放基质的研究，并探讨了淀粉基材料的广泛应用。纳入淀粉基质中的生物活性化合物的关键应用领域之一是制药行业，尤其是在口腔崩解膜方面。包装行业也对使用淀粉膜表现出极大兴趣，特别是那些具有抗氧化活性的淀粉膜。在食品技术方面，淀粉可用作纳米乳液的稳定剂，从而使生物活性化合物能够纳入各种食品类型中。淀粉在化妆品行业作为一种递送系统也具有潜力。然而，仍有几种行业可以从纳入含有生物活性化合物的淀粉基质中受益，本综述对此进行了描述。此外，在淀粉基质中使用微生物生物活性化合物代表了一个几乎未被探索的领域，仍有待研究。
