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2020年厄瓜多尔新冠疫情期间儿童常规免疫规划——潜在影响、可预测后果

Routine Immunization Programs for Children during the COVID-19 Pandemic in Ecuador, 2020-Hidden Effects, Predictable Consequences.

作者信息

Suárez-Rodríguez Gianina Lizeth, Salazar-Loor José, Rivas-Condo Jackson, Rodríguez-Morales Alfonso J, Navarro Juan-Carlos, Ramírez-Iglesias José Rubén

机构信息

Research Group of Emerging and Neglected Diseases, Ecoepidemiology and Biodiversity, Health Sciences Faculty, Universidad Internacional SEK (UISEK), Quito 170120, Ecuador.

Program of Master in Biomedicine, Health Sciences Faculty, Universidad Internacional SEK (UISEK), Quito 170120, Ecuador.

出版信息

Vaccines (Basel). 2022 May 27;10(6):857. doi: 10.3390/vaccines10060857.

Abstract

The COVID-19 pandemic has led to a global disruption of several services, including routine immunizations. This effect has been described in several countries, but there are few detailed studies in Latin America and no reports in Ecuador. Therefore, this work aims to quantify the reduction in routine immunizations for infants during the 2020 COVID-19 pandemic in Ecuador. 2018, 2019, and 2020 data were obtained from the Ministry of Health, Ecuador. The number of doses and the extent of immunization coverage was descriptively compared for four vaccines: rotavirus (ROTA), poliovirus (PV), pneumococcal (PCV), and pentavalent (PENTA) vaccines. There was no significant difference in doses applied during the 2018 and 2019 years. However, a significant (p < 0.05) drop of 137,000 delivered doses was observed in 2020 compared to the pre-pandemic years. Reductions in the percentage of coverage were more pronounced for the PENTA vaccine (17.7%), followed by PV (16.4%), ROTA (12%), and PCV vaccines (10.7%). Spatial analysis shows a severe impact on vaccination coverage on provinces from the Coast and Highland regions of the country. The pandemic has significantly impacted the immunization programs for infants across Ecuador. This retrospective analysis shows an urgent need to protect vulnerable zones and populations during public health emergencies.

摘要

新冠疫情导致包括常规免疫接种在内的多项服务在全球范围内中断。这种影响在多个国家都有描述,但在拉丁美洲的详细研究较少,在厄瓜多尔则尚无相关报告。因此,本研究旨在量化2020年厄瓜多尔新冠疫情期间婴儿常规免疫接种的减少情况。2018年、2019年和2020年的数据来自厄瓜多尔卫生部。对四种疫苗:轮状病毒疫苗(ROTA)、脊髓灰质炎病毒疫苗(PV)、肺炎球菌疫苗(PCV)和五价疫苗(PENTA)的接种剂量和免疫接种覆盖率进行了描述性比较。2018年和2019年的接种剂量没有显著差异。然而,与疫情前的年份相比,2020年观察到接种剂量显著下降(p<0.05),减少了137,000剂。五价疫苗的覆盖率下降更为明显(17.7%),其次是脊髓灰质炎病毒疫苗(16.4%)、轮状病毒疫苗(12%)和肺炎球菌疫苗(10.7%)。空间分析显示,该国沿海和高地地区的省份的疫苗接种覆盖率受到严重影响。疫情对厄瓜多尔各地的婴儿免疫计划产生了重大影响。这项回顾性分析表明,在突发公共卫生事件期间,迫切需要保护脆弱地区和人群。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1462/9227181/d2223e7e01e4/vaccines-10-00857-g001.jpg

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