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新冠疫情如何影响儿童常规疫苗接种:一项综合综述

How the COVID-19 pandemic affected routine child vaccination: an integrative review.

作者信息

Moré Julia Stoeterau, Serbena Daniel Rodrigo, Camargo Luiz Gustavo Gusson de, Clemente Pedro Augusto, Santos Fernando Sluchensci Dos, Bonini Juliana Sartori

机构信息

Laboratório de Neurociências e Comportamento, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil.

出版信息

Einstein (Sao Paulo). 2025 Mar 24;23:eRW1119. doi: 10.31744/einstein_journal/2025RW1119. eCollection 2025.

Abstract

BACKGROUND

Child immunization plays a critical role in preventing numerous diseases. However, the COVID-19) pandemic has profoundly disrupted healthcare systems globally, including routine child vaccination programs.

OBJECTIVE

To provide an overview of the reduction in vaccine coverage among infants and children during the pandemic and analyze the potential impacts of decreased child immunization during this period.

METHODS

A comprehensive search was conducted using the MeSH terms "Child," "Vaccination", and "COVID-19," along with their synonyms. Systematic reviews published between March 11, 2020, and June 1, 2023, in Portuguese or English were included. Databases searched included PubMed, BVS (Biblioteca Virtual em Saúde), Embase, and Scopus. Two blinded independent reviewers performed the selection process, with conflicts resolved by a third reviewer. The AMSTAR-II tool was used to assess the methodological quality of the included studies.

RESULTS

Of the 1,534 eligible articles, only 13 addressed the pandemic's impact on children's vaccination coverage. Most studies involved multiple countries and reported a significant decrease in children's vaccination coverage due to the COVID-19 pandemic.

CONCLUSION

The findings were heterogeneous but consistently highlighted the substantial impact of the COVID-19 pandemic on routine vaccination coverage in most countries. Further research is needed to explore the epidemiological consequences of disruptions to vaccination schedules, potentially guiding public policies and raising awareness about the importance of adhering to health protection programs.

摘要

背景

儿童免疫接种在预防多种疾病方面发挥着关键作用。然而,新冠疫情已对全球医疗系统造成了严重破坏,包括常规儿童疫苗接种计划。

目的

概述疫情期间婴幼儿疫苗接种覆盖率的下降情况,并分析这一时期儿童免疫接种减少的潜在影响。

方法

使用医学主题词“儿童”、“疫苗接种”和“新冠”及其同义词进行全面检索。纳入2020年3月11日至2023年6月1日期间以葡萄牙语或英语发表的系统评价。检索的数据库包括PubMed、BVS(虚拟健康图书馆)、Embase和Scopus。由两名盲法独立评审员进行筛选过程,如有冲突则由第三名评审员解决。使用AMSTAR-II工具评估纳入研究的方法学质量。

结果

在1534篇符合条件的文章中,只有13篇涉及疫情对儿童疫苗接种覆盖率的影响。大多数研究涉及多个国家,并报告称由于新冠疫情,儿童疫苗接种覆盖率显著下降。

结论

研究结果存在异质性,但一致强调了新冠疫情对大多数国家常规疫苗接种覆盖率的重大影响。需要进一步研究以探讨疫苗接种计划中断的流行病学后果,这可能为公共政策提供指导,并提高人们对坚持健康保护计划重要性的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67cc/11991735/acae027403c1/2317-6385-eins-23-eRW1119-gf01.jpg

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