Jefferies Meryem, Rashid Harunor, Graham Robert, Read Scott, Banik Gouri R, Lam Thao, Njiomegnie Gaitan F, Eslam Mohammed, Zhao Xiaojing, Ahmed Nausheen, Douglas Mark W, George Jacob
Western Sydney Local Health District Drug Health, North Parramatta, NSW 2151, Australia.
Storr Liver Centre, The Westmead Institute for Medical Research, The University of Sydney and Westmead Hospital, Westmead, NSW 2145, Australia.
Vaccines (Basel). 2022 Jun 1;10(6):889. doi: 10.3390/vaccines10060889.
Background: In this study, we determined the impact of the COVID-19 pandemic on Western Sydney patients with substance use disorders (SUD) by comparing emergency department (ED) admission rates before and after the onset of the COVID-19 pandemic and before the rollout of COVID-19 vaccination. Methods: ED admission data for patients with SUD were retrieved from the local electronic medical record (eMR) on the hospital central database. ED data collected from 25 January to 25 July 2019 (before the COVID-19 pandemic) were compared with data from 25 January to 25 July 2020 (early pandemic). ED admission reasons were categorised based on the presenting complaints and ED diagnoses. Results: Despite an overall reduction in ED admissions during the early pandemic, compared to the pre-pandemic period, admissions for patients with SUD increased significantly (1.7% to 3.4%, p < 0.01). ED admission rates related to infection (0.05% to 0.12%, p < 0.01), local infection (0.02% to 0.05%, p < 0.01), trauma (0.06% to 0.12%, p < 0.01), alcohol (0.01% to 0.03%, p < 0.05), and other issues (0.06% to 0.10%, p < 0.05) increased significantly among Indigenous patients with SUD. ED admission rates related to drugs (0.12% to 0.39%, p < 0.01), infection (0.21% to 0.34%, p < 0.01), local infection (0.07% to 0.18%, p < 0.01), gastrointestinal (0.15% to 0.23%, p < 0.05), trauma (0.14% to 0.25%, p < 0.01), alcohol (0.36% to 0.74%, p < 0.01), and ‘other’ issues (0.47% to 0.91%, p < 0.01) increased significantly among non-Indigenous patients with SUD. Four cases of COVID-19 were reported among these patients. Conclusions: There was an increase in ED admissions for patients with SUD in the initial six months of the COVID-19 pandemic (before vaccine rollout), mainly for drugs, systemic infection, local infection, trauma, and alcohol-related reasons. Now that most people in New South Wales have been vaccinated against COVID-19, a further study is needed to quantify the effect of the pandemic on patients with SUD in the post-vaccine era.
在本研究中,我们通过比较2019冠状病毒病大流行开始前、2019冠状病毒病疫苗推出前以及大流行开始后急诊科(ED)的入院率,确定了2019冠状病毒病大流行对悉尼西部物质使用障碍(SUD)患者的影响。方法:从医院中央数据库的本地电子病历(eMR)中检索SUD患者的ED入院数据。将2019年1月25日至7月25日(2019冠状病毒病大流行前)收集的ED数据与2020年1月25日至7月25日(大流行早期)的数据进行比较。根据就诊主诉和ED诊断对ED入院原因进行分类。结果:尽管在大流行早期ED入院总数有所减少,但与大流行前相比,SUD患者的入院人数显著增加(从1.7%增至3.4%,p<0.01)。在患有SUD的原住民患者中,与感染相关(从0.05%增至0.12%,p<0.01)、局部感染相关(从0.02%增至0.05%,p<0.01)、创伤相关(从0.06%增至0.12%,p<0.01)、酒精相关(从0.01%增至0.03%,p<0.05)以及其他问题相关(从0.06%增至0.10%,p<0.05)的ED入院率显著上升。在患有SUD的非原住民患者中,与药物相关(从0.12%增至0.39%,p<0.01)、感染相关(从0.21%增至0.34%,p<0.01)、局部感染相关(从0.07%增至0.18%,p<0.01)、胃肠道相关(从0.15%增至0.23%,p<0.05)、创伤相关(从0.14%增至0.25%,p<0.01)、酒精相关(从0.36%增至0.74%,p<0.01)以及“其他”问题相关(从0.47%增至0.91%,p<0.01)的ED入院率显著上升。这些患者中报告了4例2019冠状病毒病病例。结论:在2019冠状病毒病大流行的最初六个月(疫苗推出前),SUD患者的ED入院人数增加,主要原因是药物、全身感染、局部感染、创伤和酒精相关问题。鉴于新南威尔士州的大多数人已接种2019冠状病毒病疫苗,需要进一步研究以量化大流行在疫苗接种后时代对SUD患者的影响。