Suppr超能文献

减轻不相容昆虫技术下建立种群的策略。

Strategies to Mitigate Establishment under the Incompatible Insect Technique.

机构信息

Environmental Health Institute, National Environment Agency, Singapore 138667, Singapore.

Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore 117549, Singapore.

出版信息

Viruses. 2022 May 24;14(6):1132. doi: 10.3390/v14061132.

Abstract

The Incompatible Insect Technique (IIT) strategy involves the release of male mosquitoes infected with the bacterium . Regular releases of male -infected mosquitoes can lead to the suppression of mosquito populations, thereby reducing the risk of transmission of vector-borne diseases such as dengue. However, due to imperfect sex-sorting under IIT, fertile -infected female mosquitoes may potentially be unintentionally released into the environment, which may result in replacement and failure to suppress the mosquito populations. As such, mitigating establishment requires a combination of IIT with other strategies. We introduced a simple compartmental model to simulate ex-ante mosquito population dynamics subjected to a -IIT programme. In silico, we explored the risk of replacement, and strategies that could mitigate the establishment of the released strain in the mosquito population. Our results suggest that mitigation may be achieved through the application of a sterile insect technique. Our simulations indicate that these interventions do not override the intended wild type suppression of the IIT approach. These findings will inform policy makers of possible ways to mitigate the potential establishment of using the IIT population control strategy.

摘要

不兼容昆虫技术(IIT)策略涉及释放感染细菌的雄性蚊子。定期释放感染雄性的蚊子可以抑制蚊子种群,从而降低登革热等媒介传播疾病的传播风险。然而,由于 IIT 下不完全的性别分类,有生育能力的感染雌性蚊子可能会被意外释放到环境中,这可能导致替代和未能抑制蚊子种群。因此,减轻建立需要将 IIT 与其他策略相结合。我们引入了一个简单的隔室模型来模拟受到 -IIT 计划的蚊子种群动态。在计算机模拟中,我们探讨了替代的风险,以及可以减轻释放菌株在蚊子种群中建立的策略。我们的结果表明,通过应用不育昆虫技术可以实现缓解。我们的模拟表明,这些干预措施并没有超越 IIT 方法对野生型的预期抑制。这些发现将为决策者提供使用 IIT 种群控制策略减轻 的潜在建立的可能方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb92/9229438/7796732adce6/viruses-14-01132-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验