Prakash Sameer, Merza Nooraldin, Hosseini Omid, Ward Haven, Mansi Tarek, Balducci Michelle, Trammell Deborah, Hernandez Brenda, Obokhare Izi
Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, USA.
Internal Medicine, Memorial Hermann The Woodlands Hospital, Spring, USA.
Cureus. 2022 May 20;14(5):e25169. doi: 10.7759/cureus.25169. eCollection 2022 May.
Background The incidence of colorectal cancer (CRC) in the United States is increasing. It remains the second leading cause of cancer death in the United States for men and women combined, mainly due to underutilization of screening methods. The American Cancer Society now recommends that adults aged 45 years and older with an average risk of CRC undergo regular screening with either a high-sensitivity stool-based test or structural (visual) examination, depending on patient preference and test availability. The primary objective of this quality improvement project was to determine if reminder methods, such as telephone or letter reminders, increased the return rate of fecal immunochemical tests (FIT) for CRC screening. Methodology At public outreach events and daily clinics in the West Texas Panhandle area, participants in the GET FIT program were provided with FIT kits after completing the education on CRC. Participants who fit the inclusion criteria and had received a FIT kit from the program were included. They were instructed on how to perform the test and mail it back. Participants who did not return the completed kits within two weeks were reminded either through (1) a reminder letter, (2) telephone, or (3) a combination of letter reminder and telephone call every two weeks (±three days) for 60 days or five attempts to contact. We de-identified and analyzed the FIT kit return data from April-September 2019 before analyzing these reminder methods. We then calculated the change in return rates from October 2019 to March 2020. Our goal was to increase the FIT return rates by 25% compared to the baseline return rate. Results The pre-intervention return rate of kits for April-September 2019 was 61.52%, and the post-intervention return rate for October 2019-March 2020 was 71.85%. This rate was equal to an approximately 16.79% increase in return rates that was statistically significant (p < 0.01). There was a significant difference in the method of reminder between the two groups, but no significant differences in gender and race/ethnicity between the two groups. There was a significant difference in return rates between race/ethnicities in the October-March cohort with black and Hispanic participants having the highest return rates of 82.3% and 77.25%, respectively. Conclusions FIT remains one of the primary options for CRC screening. Due to its lower cost and noninvasiveness, FIT was offered to patients at average risk. We demonstrated an increase in return rates, although we did not meet our target return rate goal for this project. This study was limited due to a gradual increase in coronavirus disease 2019 (COVID-19) cases and a subsequent shift and conversation of ongoing research into COVID-19.
美国结直肠癌(CRC)的发病率正在上升。它仍是美国男性和女性综合癌症死亡的第二大主要原因,主要是由于筛查方法的使用不足。美国癌症协会现在建议,45岁及以上且患CRC平均风险的成年人根据患者偏好和检测可用性,通过高灵敏度粪便检测或结构性(视觉)检查进行定期筛查。这个质量改进项目的主要目标是确定提醒方法,如电话或信件提醒,是否能提高用于CRC筛查的粪便免疫化学检测(FIT)的回收率。
在西德克萨斯狭长地带地区的公共宣传活动和日常诊所中,“变得健康”项目的参与者在完成关于CRC的教育后会获得FIT检测试剂盒。符合纳入标准且从该项目中获得FIT检测试剂盒的参与者被纳入研究。他们被告知如何进行检测并寄回。在两周内未寄回已完成试剂盒的参与者,每两周(±3天)通过(1)提醒信、(2)电话或(3)信件提醒和电话相结合的方式被提醒60天或进行5次联系尝试。在分析这些提醒方法之前,我们对2019年4月至9月的FIT检测试剂盒回收数据进行了去识别和分析。然后我们计算了2019年10月至2020年3月回收率的变化。我们的目标是使FIT回收率相比基线回收率提高25%。
2019年4月至9月试剂盒的干预前回收率为61.52%,2019年10月至2020年3月的干预后回收率为71.85%。这个回收率相当于回收率提高了约16.79%,具有统计学意义(p < 0.01)。两组之间的提醒方式存在显著差异,但两组之间在性别和种族/族裔方面没有显著差异。在10月至3月的队列中,不同种族/族裔的回收率存在显著差异,黑人和西班牙裔参与者的回收率最高,分别为82.3%和77.25%。
FIT仍然是CRC筛查的主要选择之一。由于其成本较低且无创,FIT被提供给平均风险的患者。我们证明了回收率有所提高,尽管我们没有达到该项目的目标回收率。由于2019冠状病毒病(COVID - 19)病例逐渐增加,以及正在进行的研究随后转向并聚焦于COVID - 19,本研究受到了限制。