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心包外脂肪坏死:文献综述

Epipericardial Fat Necrosis: A Concise Review of Literature.

作者信息

Zafar Meer R, Mustafa Syed Farrukh, Shahbaz Amir, Warraich Sami, Altaf Areeba

机构信息

Internal Medicine, Sisters of Charity Hospital, Buffalo, USA.

Internal Medicine, Jacobs School of Medicine and Biomedical Sciences, Buffalo, USA.

出版信息

Cureus. 2021 Feb 3;13(2):e13106. doi: 10.7759/cureus.13106.

DOI:10.7759/cureus.13106
PMID:33728126
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7935229/
Abstract

Epipericardial fat necrosis (EFN) is an inflammatory process that occurs in the mediastinal fat surrounding the heart. It is a rare cause of acute chest pain and mimics more ominous clinical conditions such as acute coronary syndrome, aortic dissection, and pulmonary embolism. Clinicians are often not familiar with this condition due to its infrequent occurrence, and traditional textbooks of medicine and cardiology have not covered this topic adequately. In the past, EFN had been managed primarily with thoracotomy and surgical excision. This has changed with advances in imaging techniques and their more frequent utilization. Computed tomography (CT) of the chest is essential for the diagnosis of EFN as it allows for the evaluation of the nature and precise location of the lesion. Magnetic resonance imaging helps to differentiate EFN from other mediastinal fatty lesions such as lipomas or liposarcomas. The clinical presentation of acute chest pain along with CT findings of the encapsulated fatty pericardial lesion is adequate for diagnosis. Our review describes the emerging role of imaging in diagnosis and change in management over the last few years.

摘要

心包外脂肪坏死(EFN)是一种发生在心脏周围纵隔脂肪中的炎症过程。它是急性胸痛的罕见原因,可模拟更严重的临床病症,如急性冠状动脉综合征、主动脉夹层和肺栓塞。由于其发病率低,临床医生通常对这种病症并不熟悉,传统的医学和心脏病学教科书也没有充分涵盖这一主题。过去,EFN主要通过开胸手术和手术切除进行治疗。随着成像技术的进步及其更频繁的应用,这种情况已经发生了变化。胸部计算机断层扫描(CT)对于EFN的诊断至关重要,因为它可以评估病变的性质和精确位置。磁共振成像有助于将EFN与其他纵隔脂肪病变,如脂肪瘤或脂肪肉瘤区分开来。急性胸痛的临床表现以及包裹性脂肪心包病变的CT表现足以确诊。我们的综述描述了成像在诊断中的新兴作用以及过去几年管理方式的变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5988/7935229/f554cdd9d93c/cureus-0013-00000013106-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5988/7935229/59f11e2bb86d/cureus-0013-00000013106-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5988/7935229/4c7da3c43f0f/cureus-0013-00000013106-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5988/7935229/f554cdd9d93c/cureus-0013-00000013106-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5988/7935229/59f11e2bb86d/cureus-0013-00000013106-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5988/7935229/4c7da3c43f0f/cureus-0013-00000013106-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5988/7935229/f554cdd9d93c/cureus-0013-00000013106-i03.jpg

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本文引用的文献

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Am J Transplant. 2020 May;20(5):1451-1453. doi: 10.1111/ajt.15744. Epub 2020 Jan 24.
2
Fat necrosis in the Breast: A systematic review of clinical.乳房脂肪坏死:临床的系统评价。
Lipids Health Dis. 2019 Jun 11;18(1):139. doi: 10.1186/s12944-019-1078-4.
3
Epipericardial Fat Pad Necrosis-A Rare Cause of Chest Pain in an Adolescent.心外膜脂肪垫坏死——青少年胸痛的一个罕见病因。
胸痛的复杂诊断:冠状动脉计算机断层扫描的重要作用
Neth Heart J. 2025 Jan;33(1):34-35. doi: 10.1007/s12471-024-01889-1. Epub 2024 Aug 8.
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Epipericardial fat necrosis as a differential diagnosis of acute chest pain: a case report and algorithm proposal for diagnostic approach.心外膜脂肪坏死作为急性胸痛的鉴别诊断:病例报告及诊断方法的算法建议。
Einstein (Sao Paulo). 2023 May 29;21:eRC0183. doi: 10.31744/einstein_journal/2023RC0183. eCollection 2023.
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Epipericardial fat necrosis: a case report of an underdiagnosed disease.心包外脂肪坏死:一例诊断不足疾病的病例报告
Porto Biomed J. 2023 Apr 10;8(2):e205. doi: 10.1097/j.pbj.0000000000000205. eCollection 2023 Mar-Apr.
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