用于合成6-菲啶衍生物的NHC-醇加合物介导的光催化脱氧反应
NHC-alcohol adduct-mediated photocatalytic deoxygenation for the synthesis of 6-phenanthridine derivatives.
作者信息
Ma Xueji, Wang Qingyun, Wu Jinge, Zhang Liyuan, Sun Aili, Wang Zhanyong
机构信息
School of Pharmacy, Key Laboratory of Nano-carbon Modified Film Technology Engineering of Henan Province, Xinxiang University, Xinxiang 453000, P. R. China.
出版信息
Org Biomol Chem. 2022 Jul 13;20(27):5393-5396. doi: 10.1039/d2ob00814a.
NHC-alcohol adduct-mediated deoxygenation of alcohols under photocatalytic conditions is described. This process provides various alkyl radicals, which can react with 2-isocyanobiaryls to afford 6-substituted phenanthridine derivatives in moderate to good yields. This method offered the first example of directly using alcohols as radical sources for 6-phenanthridine synthesis.
描述了在光催化条件下NHC-醇加合物介导的醇脱氧反应。该过程产生各种烷基自由基，这些自由基可与2-异氰基联芳基反应，以中等至良好的产率得到6-取代菲啶衍生物。该方法为直接使用醇作为6-菲啶合成的自由基源提供了首个实例。
Zotero 插件