Biology and Endodontics: Thinking Outside the Box.

Combining evidence-based dentistry (EBD) with years of clinician experience should have a great impact on treatment planning and decision-making for achieving the best treatment outcomes, thus warranting patient satisfaction. In addition, understanding and appreciating the role of biology on the reliance on and progress of treatment healing is also a crucial element that clinicians should always keep in mind in their dental practice. This study demonstrates that clinicians should always rely on their own clinical and radiographical test results for evaluation and judgment of any clinical situation before presenting and proceeding with any dental treatment for their patients.