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在三级医疗中心评估计算机断层扫描上的肺动脉高压征象并与超声心动图进行相关性研究

Evaluating Signs of Pulmonary Hypertension on Computed Tomography and Correlating With Echocardiography: A Study at a Tertiary Care Hospital.

作者信息

Rehman Abdur, Darira Jaideep, Ahmed Muhammad Saad, Hamid Kamran, Shazlee Muhammad Kashif, Hyder Syed Muhammad Shahnawaz

机构信息

Radiology, Dr. Ziauddin Hospital, Karachi, PAK.

Diagnostic Radiology, Dr. Ziauddin Hospital, Karachi, PAK.

出版信息

Cureus. 2022 May 25;14(5):e25319. doi: 10.7759/cureus.25319. eCollection 2022 May.

Abstract

INTRODUCTION

Pulmonary hypertension (PH) is a threatening condition, and it is far more common than previously assumed, especially after the COVID pandemic. Its outcome is not good; if detected late, and can lead to right ventricular failure, which can be fatal. Our goal was to evaluate CT signs of PH, correlate them with echocardiography, and identify the cut-off values of these signs in our population.

METHOD

In this study, 160 patients having both CT and echocardiography with a maximum gap of one month were assessed from June to November 2021. The association between CT signs and echocardiography to diagnose PH was investigated. The Pearson and Spearman correlation and area under receiver operating curve (AUROC) tests were performed in the analysis. Receiver operating characteristic curve analysis was also used to assess CT's diagnostic capability and cut-off values.

RESULT

The correlation between main pulmonary artery (MPA) diameter and main pulmonary artery to aorta ratio (MPA/AO) with mean pulmonary artery pressure (mPAP) was weak but statistically significant (r = 0.316 and r = 0.321, p<0.001). However, there was a very weak correlation between the right and left pulmonary artery and mPAP with correlation coefficients (r) of 0.155 and 0.138, respectively. For the first time in our population, we measured the cut-off values of MPA and MPA/AO ratios for PH which were 26 and 0.88 mm, respectively.

CONCLUSIONS

The CT signs of PH correlate with echocardiography; however, should not be used solely; the cut-off values should be used according to race and population.

摘要

引言

肺动脉高压(PH)是一种威胁生命的疾病,其发病率比之前认为的要高得多,尤其是在新冠疫情之后。其预后不佳,如果发现较晚,可能会导致右心室衰竭,甚至危及生命。我们的目标是评估PH的CT征象,将其与超声心动图进行关联,并确定这些征象在我们研究人群中的临界值。

方法

本研究纳入了2021年6月至11月期间160例接受了CT和超声心动图检查且两次检查间隔最长为1个月的患者。研究了CT征象与超声心动图诊断PH之间的关联。分析中进行了Pearson和Spearman相关性分析以及受试者工作特征曲线下面积(AUROC)检验。还使用受试者工作特征曲线分析来评估CT的诊断能力和临界值。

结果

主肺动脉(MPA)直径和主肺动脉与主动脉比值(MPA/AO)与平均肺动脉压(mPAP)之间的相关性较弱,但具有统计学意义(r = 0.316和r = 0.321,p<0.001)。然而,左右肺动脉与mPAP之间的相关性非常弱,相关系数(r)分别为0.155和0.138。我们首次在研究人群中测量了PH的MPA和MPA/AO比值的临界值,分别为26和0.88 mm。

结论

PH的CT征象与超声心动图相关;然而,不应单独使用;应根据种族和人群使用临界值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4ff/9231577/ca74a969dd13/cureus-0014-00000025319-i01.jpg

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