复原力调节成年志愿者睡眠障碍及睡眠反应性与抑郁症状之间的关联。
Resilience Moderates the Association of Sleep Disturbance and Sleep Reactivity with Depressive Symptoms in Adult Volunteers.
作者信息
Terao Itsuki, Masuya Jiro, Morishita Chihiro, Higashiyama Motoki, Shimura Akiyoshi, Tamada Yu, Inoue Takeshi, Fujimura Yota
机构信息
Department of Psychiatry, Tokyo Medical University, Tokyo, Japan.
Department of Psychiatry, Toranomon Hospital Kajigaya, Kawasaki, Kanagawa, Japan.
出版信息
Neuropsychiatr Dis Treat. 2022 Jun 20;18:1249-1257. doi: 10.2147/NDT.S361353. eCollection 2022.
PURPOSE
Depression poses a substantial burden worldwide. Therefore, elucidating the pathophysiological mechanism of depression is important. Sleep disturbance and sleep reactivity are symptoms of depression and are also known to exacerbate depressive symptoms. On the other hand, it is well known that resilience ameliorates depressive symptoms. To our knowledge, there have been no reports to date regarding the interaction effects among sleep disturbance, sleep reactivity, and resilience on depressive symptoms. We hypothesized that resilience buffers the aggravating effects of sleep disturbance and sleep reactivity on depressive symptoms. To test this hypothesis, we conducted hierarchical multiple regression analyses.
SUBJECTS AND METHODS
A total of 584 Japanese adult volunteers were recruited between April 2017 and April 2018 by convenience sampling. Their demographic characteristics, sleep disturbance, sleep reactivity, resilience, and depressive symptoms were investigated using self-administered questionnaires. The data were analyzed using hierarchical multiple regression analyses.
RESULTS
Sleep disturbance and sleep reactivity were significantly positively associated with depressive symptoms, whereas resilience was significantly negatively associated with depressive symptoms. Moreover, there was a significant interaction between sleep disturbance or sleep reactivity and resilience on depressive symptoms. Resilience significantly alleviated the aggravating effect of sleep disturbance and sleep reactivity on depressive symptoms.
CONCLUSION
Our results indicate that people with lower resilience have more severe depressive symptoms that are associated with sleep disturbance and sleep reactivity. Therefore, there is a possibility that the enhancement of resilience will buffer the aggravating effects of sleep disturbance and sleep reactivity on depressive symptoms, and that improving sleep quality might alleviate the negative effect of low resilience on depressive symptoms.
目的
抑郁症在全球范围内造成了沉重负担。因此，阐明抑郁症的病理生理机制很重要。睡眠障碍和睡眠反应性是抑郁症的症状，并且已知会加重抑郁症状。另一方面，众所周知，心理韧性可改善抑郁症状。据我们所知，迄今为止尚无关于睡眠障碍、睡眠反应性和心理韧性对抑郁症状的交互作用的报道。我们假设心理韧性可缓冲睡眠障碍和睡眠反应性对抑郁症状的加重作用。为验证这一假设，我们进行了分层多元回归分析。
对象与方法
2017年4月至2018年4月期间，通过便利抽样招募了584名日本成年志愿者。使用自填式问卷对他们的人口统计学特征、睡眠障碍、睡眠反应性、心理韧性和抑郁症状进行了调查。采用分层多元回归分析对数据进行分析。
结果
睡眠障碍和睡眠反应性与抑郁症状显著正相关，而心理韧性与抑郁症状显著负相关。此外，睡眠障碍或睡眠反应性与心理韧性在抑郁症状上存在显著交互作用。心理韧性显著减轻了睡眠障碍和睡眠反应性对抑郁症状的加重作用。
结论
我们的结果表明，心理韧性较低的人抑郁症状更严重，且与睡眠障碍和睡眠反应性有关。因此，增强心理韧性有可能缓冲睡眠障碍和睡眠反应性对抑郁症状的加重作用，改善睡眠质量可能减轻心理韧性低对抑郁症状的负面影响。
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