Carena M, Aprile C, Zelaschi G P, Rossi G, Paroni G, Campini R
Radiol Med. 1987 Apr;73(4):310-2.
The aim of this work has been the study of the mechanism of lymph formation and drainage in the upper limb in patients with monolateral lymphoedema (15 limbs, L) in comparison with the apparently healthy limb (S) as well as with a control group (8 limbs, C). After interstitial injection of 99mTc sulphur micro-colloid, scans were obtained employing a LFOV camera linked to a data processor. Results were expressed as percentage of the id removed from the injection site 1 and 6 hr pi, mean T6%/h it is (T6-T1)/5 and percentage lymph nodes uptake at the same times. Mean T6%/h is significantly different between C and L, but not between L and S, while lymph node uptake at 6 hr shows a significant difference even between C and S. Quantitative lymphoscintigraphy appears to be a feasible indicator of early changes in the lymph pathophysiology and supports the hypothesis that lymphoedema generally arises from a predisposing congenital pathology.
本研究旨在探讨单侧淋巴水肿患者（15条患肢，L组）上肢淋巴形成和引流机制，与健侧上肢（S组）以及对照组（8条肢体，C组）进行比较。在间质注射99mTc硫微胶体后，使用与数据处理器相连的大视野相机进行扫描。结果以注射后1小时和6小时从注射部位清除的标记物百分比、平均每小时清除率（T6%/h，即(T6 - T1)/5）以及同一时间的淋巴结摄取百分比表示。C组和L组之间平均T6%/h有显著差异，但L组和S组之间无显著差异，而6小时时的淋巴结摄取率即使在C组和S组之间也有显著差异。定量淋巴闪烁显像似乎是淋巴病理生理学早期变化的一个可行指标，并支持淋巴水肿通常由先天性易感病理引起的假说。
