Carena M, Campini R, Zelaschi G, Rossi G, Aprile C, Paroni G
Department of Nuclear Medicine, Fondazione Clinica del Lavoro, Pavia, Italy.
Eur J Nucl Med. 1988;14(2):88-92. doi: 10.1007/BF00253447.
A radioisotopic method was used to evaluate the state and dynamics of the lymphatic system in 92 patients affected by chronic oedema of the limbs and in 12 control subjects. After interstitial injections of 99mTc-sulphur microcolloid, scans were obtained using a LFOV camera linked to a data processor. The quantitative indices of clearance and lymph node uptake obtained showed good correlation with lymphoedema etiology, controls and ostensibly healthy limbs of patients affected by monolateral disease. In conclusion, quantitative lymphoscintigraphy appears to be a feasible indicator of early changes in the lymph pathophysiology and supports the hypothesis that lymphoedema generally arises from a predisposing congenital pathology.
采用放射性同位素方法对92例肢体慢性水肿患者及12例对照者的淋巴系统状态和动力学进行评估。在间质注射99m锝-硫微胶体后，使用与数据处理器相连的大视野相机进行扫描。所获得的清除率和淋巴结摄取的定量指标与淋巴水肿病因、对照组以及单侧疾病患者表面健康的肢体具有良好的相关性。总之，定量淋巴闪烁显像似乎是淋巴病理生理学早期变化的可行指标，并支持淋巴水肿通常源于先天性易患病理的假说。
