Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Harvard Radiation Oncology Program, Boston, Massachusetts, USA.
Neuro Oncol. 2022 Oct 3;24(10):1613-1646. doi: 10.1093/neuonc/noac118.
Brain metastases occur commonly in patients with advanced solid malignancies. Yet, less is known about brain metastases than cancer-related entities of similar incidence. Advances in oncologic care have heightened the importance of intracranial management. Here, in this consensus review supported by the Society for Neuro-Oncology (SNO), we review the landscape of brain metastases with particular attention to management approaches and ongoing efforts with potential to shape future paradigms of care. Each coauthor carried an area of expertise within the field of brain metastases and initially composed, edited, or reviewed their specific subsection of interest. After each subsection was accordingly written, multiple drafts of the manuscript were circulated to the entire list of authors for group discussion and feedback. The hope is that the these consensus guidelines will accelerate progress in the understanding and management of patients with brain metastases, and highlight key areas in need of further exploration that will lead to dedicated trials and other research investigations designed to advance the field.
脑转移瘤常见于晚期实体恶性肿瘤患者。然而，人们对脑转移瘤的了解却不如发病率相似的癌症相关实体瘤。肿瘤治疗的进展提高了颅内管理的重要性。在这里，在神经肿瘤学学会（SNO）的支持下，我们对脑转移瘤的现状进行了综述，特别关注了管理方法和潜在的未来治疗模式。每位合著者在脑转移瘤领域都有专业知识，最初撰写、编辑或审查了他们感兴趣的特定部分。在相应地完成每个小节的写作后，将手稿的多个草稿分发给所有作者进行小组讨论和反馈。希望这些共识指南将加速对脑转移瘤患者的理解和管理方面的进展，并强调需要进一步探索的关键领域，这将导致专门的试验和其他旨在推进该领域的研究调查。
