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[墨西哥社会保障局行政人员中抗严重急性呼吸综合征冠状病毒2血清流行率]

[Anti-SARS-CoV-2 seroprevalence in administrative staff of the Mexican Institute for Social Security].

作者信息

Cedeño-Cuellar María Cristina, Luna-Vargas Ana Karen, García-Hernández Erendira Tonantzin, Vargas-Madrid Silvia Yolanda, Sánchez-Cañas José Alberto, Galván-Bobadilla Alexis Ignacio, Cuevas-García Carlos Fredy, Benítez-Arvizu Gamaliel

机构信息

Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Servicio de Medicina Interna. Ciudad de México, México.

Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades"Dr. Bernardo Sepúlveda Gutiérrez", Banco de Sangre. Ciudad de México, México.

出版信息

Rev Med Inst Mex Seguro Soc. 2022 May 2;60(3):297-303.

Abstract

BACKGROUND

Asymptomatic subjects, the lack of diagnostic tests and, in countries like Mexico, the epidemiological surveillance method does not allow to establish the real number of infections in the COVID-19 pandemic. Frontline health personnel, as well as other groups related to priority activities are considered of high risk. We included administrative workers in contact with health personnel in the hospital units of the Mexican Institute for Social Security (IMSS, according to its initials in Spanish).

OBJECTIVE

To identify the seroprevalence of antibodies to SARS-CoV-2 in IMSS' administrative staff who does not treat patients.

MATERIAL AND METHODS

76 volunteer participating individuals were incluided; IgG antibodies against the SARS-CoV-2 nucleoprotein were measured. A questionnaire was administered to the participants in order to identify possible risk factors.

RESULTS

76 participants were included (39 men, 51.7%), with a median age of 42 years. 29 out of 76 subjects (38.2%), whose median age was 38 years (range 18-69 years); 15 men (51.7%), and 14 women (48.3%). A higher percentage of positive subjects under 45 years of age (n = 20, 84.2%) was observed than those aged 45 or over (n = 9, 25%), with an OR of 3 (95% CI 1.13-7.96, p = 0.03). No statistically significant difference was found regarding the type of comorbidity.

CONCLUSIONS

The prevalence identified shows an important circulation of the virus in the administrative staff.

摘要

背景

在新冠疫情中,无症状感染者、缺乏诊断检测手段,以及在墨西哥等国家,流行病学监测方法无法确定实际感染人数。一线卫生人员以及与优先活动相关的其他群体被视为高风险人群。我们纳入了墨西哥社会保障局(IMSS,西班牙语首字母缩写)医院单位中与卫生人员有接触的行政工作人员。

目的

确定墨西哥社会保障局中不接触患者的行政工作人员中抗SARS-CoV-2抗体的血清阳性率。

材料与方法

纳入76名参与研究的志愿者;检测针对SARS-CoV-2核蛋白的IgG抗体。向参与者发放问卷以确定可能的风险因素。

结果

纳入76名参与者(39名男性,占51.7%),中位年龄为42岁。76名受试者中有29名(38.2%)呈阳性,其中位年龄为38岁(范围18 - 69岁);15名男性(51.7%),14名女性(48.3%)。观察到45岁及以下的阳性受试者比例(n = 20,84.2%)高于45岁及以上者(n = 9,25%),比值比为3(95%置信区间1.13 - 7.96,p = 0.03)。在合并症类型方面未发现统计学显著差异。

结论

所确定的患病率表明该病毒在行政工作人员中有重要传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef1a/10396060/d7c599858d19/04435117-60-3-297-c001.jpg

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