Intrinsic Temporal Performance of the RF Receive Coil in Magnetic Resonance Imaging.

The functional magnetic resonance imaging (fMRI) at ultra-high field (UHF, [Formula: see text]) is a powerful temporal acquisition method which promises to capture neuronal activities at submillimeter scale. But high-spatial-resolution fMRI still remains difficult, as the nuisance temporal noise which also grows with the main magnetic field strength. For decades, mainstream solutions in reducing motion-induced temporal noise include motion-correction algorithms in image post-processing as well as MR acquisition schemes in RF pulse sequence designs, however hardware-related studies have been rarely reported over the RF receive coil. In this study, we have proposed the intrinsic temporal performance model, which is specifically used for measuring coil-related intrinsic temporal SNR (tSNR*), and the intrinsic sensitivity variability and thermal noise variability have been proposed as model parameters. The intrinsic temporal performance of single-channel loops and array coils were evaluated using numerical electromagnetic simulations, and phantom experiments were designed to investigate the intrinsic thermal noise variability. It was observed that the achievable intrinsic tSNR* can be greatly lowered by ~90% even with 2 mm translational motion in the normal direction, suggesting the effect of RF receive coils in producing temporal noise. The proposed model provides a new perspective in optimizing coil designs and array coil temporal combination methods, which may offer a feasible means in achieving submillimeter resolutions at UHF. Moreover, model parameters from the intrinsic temporal performance model can be directly calculated based on single MRI acquisition, offering a practical performance metric for manufactures and customers in quality and assurance checks of RF receive coil products.