Department of Spine Surgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221006, Jiangsu, People's Republic of China.
J Orthop Surg Res. 2022 Jun 28;17(1):336. doi: 10.1186/s13018-022-03226-x.
To explore the influence of irrigating fluid at different temperatures on patients' body temperature and local inflammatory mediators during spinal endoscopy.
110 cases of intervertebral foramen surgery in our hospital from January 2019 to October 2021 were randomly divided into control group and observation group. Operations of both groups were performed by the same experienced chief physician. The observation group was irrigated with 37 °C constant temperature saline, while the control group was irrigated at room temperature. The effect was evaluated by monitoring the intraoperative temperature, postoperative VAS score and the levels of inflammatory factors, such as TNF-α, IL-1, IL-6 and IL-10 in drainage fluid.
After 30 min of operation, overall temperature of the control group dropped significantly, and 50 cases (90.9%) had hypothermia, P < 0.05. There was no significant difference in preoperative VAS score between the two groups P > 0.05. The VAS score of observation group was significantly lower than that of control group at 6 h and 1 month after operation, P < 0.05. At 0, 3 and 6 h after operation, the values of TNF-α, IL-1, IL-6 and IL-10 in the observation group were significantly lower than those in the control group (P < 0.05).
Isothermal flushing solution can reduce the incidence of hypothermia and effectively alleviate local inflammatory reaction.
探讨脊柱内窥镜术中不同温度灌洗液对患者体温及局部炎症介质的影响。
选取我院 2019 年 1 月至 2021 年 10 月间收治的 110 例行椎间孔手术患者，随机分为对照组和观察组，每组 55 例。两组均由同一位经验丰富的主任医师进行手术。观察组采用 37℃恒温生理盐水冲洗，对照组采用室温冲洗。通过监测术中体温、术后视觉模拟评分（VAS）及引流液中 TNF-α、IL-1、IL-6、IL-10 等炎症因子水平，评估疗效。
术后 30min 时，对照组患者的总体体温明显下降，有 50 例（90.9%）出现低体温，P<0.05。两组患者术前 VAS 评分差异无统计学意义，P>0.05。术后 6h 和 1 个月时，观察组患者的 VAS 评分明显低于对照组，P<0.05。术后 0、3、6h，观察组患者的 TNF-α、IL-1、IL-6 和 IL-10 水平均明显低于对照组，P<0.05。
恒温冲洗液可降低低体温的发生率，有效缓解局部炎症反应。
