阿尔及利亚尿路感染的细菌学特征及抗生素敏感性
Bacteriological profile of urinary tract infections and antibiotic susceptibility of in Algeria.
作者信息
Ait-Mimoune Nouara, Hassaine Houda, Boulanoir Meriem
机构信息
Department of Biology, Laboratory of Microbiology, Bouira University, Bouira, Algeria.
Department of Biological Analysis, Laboratory of Bacteriology, Tizi-Ouzou Hospital, Tizi-Ouzou, Algeria.
出版信息
Iran J Microbiol. 2022 Apr;14(2):156-160. doi: 10.18502/ijm.v14i2.9180.
BACKGROUND AND OBJECTIVES
Urinary tract infections are one of the most common bacterial infections worldwide. The emergence of antibiotic-resistant bacterial strains is a serious problem and greatest challenge in public health care. The purpose of this study was to determine the prevalence of uropathogenic microorganisms and the antibiotic resistance pattern of in Algeria.
MATERIALS AND METHODS
Urine samples were collected from 760 outpatients in the hospital of Tizi-Ouzou (Algeria). From the positive cultures, 120 strains of were isolated and tested for their susceptibility to antibiotics by disk diffusion method on Mueller Hinton agar medium.
RESULTS
Among the collected urine specimens, 270 (35.5%) yielded positive cultures for urinary tract infection. Females were more affected with a sex ratio F/M of 1.14. was the most prevalent isolated bacteria with a rate of 44.44%, followed by (12.21%), (11.1%) and (5.55%). Isolates of showed high level of resistance to cephalothin (85.83%), ticarcillin (82.5%), ampicillin (73.3%) and amoxicillin-clavulanic acid (58.33%). Imipenem was the most effective antimicrobial agent.
CONCLUSION
These results highlight the inappropriate utilization of antibiotics and suggest the need to improve prescription practices in our country.
背景与目的
尿路感染是全球最常见的细菌感染之一。抗生素耐药菌株的出现是公共卫生保健领域的一个严重问题和最大挑战。本研究的目的是确定阿尔及利亚尿路致病性微生物的流行情况以及抗生素耐药模式。
材料与方法
从阿尔及利亚提济乌祖医院的760名门诊患者中收集尿液样本。从阳性培养物中分离出120株菌株，并在穆勒-欣顿琼脂培养基上通过纸片扩散法检测它们对抗生素的敏感性。
结果
在收集的尿液标本中，270份（35.5%）培养出尿路感染阳性。女性受影响更严重，男女比例为1.14。大肠埃希菌是最常见的分离细菌，比例为44.44%，其次是肺炎克雷伯菌（12.21%）、金黄色葡萄球菌（11.1%）和粪肠球菌（5.55%）。大肠埃希菌分离株对头孢噻吩（85.83%）、替卡西林（82.5%）、氨苄西林（73.3%）和阿莫西林-克拉维酸（58.33%）表现出高度耐药。亚胺培南是最有效的抗菌剂。
结论
这些结果突出了抗生素的不合理使用，并表明我国需要改进处方习惯。
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