Razavyoon Taraneh, Hashemi Seyed Jamal, Mansouri Parvin, Rafat Zahra, Saboor-Yaraghi Ali Akbar, Kamali Sarvestani Hasti, Ghasemi Zeinab
Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Iran J Microbiol. 2022 Apr;14(2):268-275. doi: 10.18502/ijm.v14i2.9196.
Onychomycosis is caused by dermatophyte species, non-dermatophyte moulds (NDMs), and accounts for roughly 50% of all nail diseases. As the prevalence of onychomycosis is increasing, new epidemiologic documents may help with treatment and prevention. The present investigation aims to determine the epidemiological profile of onychomycosis in 2 mycology laboratories.
A cross-sectional study conducted during eight months (2019-2020) on 169 patients with positive nail mycology tests referred to two mycological laboratory centers affiliated with Tehran University of Medical Science. The nail clippings were examined by direct smear and culture. Also, molecular assays were performed if needed.
10% of nail lesions referred to Razi Hospital (RH), and 30% of nail lesions referred to TUMS mycology laboratory were positive. Middle age (40-60) suffer more from onychomycosis. , and were the most common etiologic agents in each of the three main classes of fungi causing onychomycosis. Females were more infected. NDMs were the predominant etiologic agents, and toenails were the most common site of onychomycosis.
The pattern of etiologic agents and clinical signs of onychomycosis differs according to geographical region and age, so repeated epidemiological surveys of onychomycosis seem to be fundamental.
甲癣由皮肤癣菌、非皮肤癣菌霉菌(NDMs)引起,约占所有指甲疾病的50%。随着甲癣患病率的上升,新的流行病学文献可能有助于治疗和预防。本研究旨在确定两个真菌学实验室中甲癣的流行病学特征。
在八个月(2019 - 2020年)期间,对转诊至德黑兰医科大学附属的两个真菌学实验室中心的169例指甲真菌学检测呈阳性的患者进行了横断面研究。指甲剪屑通过直接涂片和培养进行检查。如有需要,还进行了分子检测。
转诊至拉齐医院(RH)的指甲病变中有10%呈阳性,转诊至德黑兰医科大学真菌学实验室的指甲病变中有30%呈阳性。中年(40 - 60岁)人群患甲癣的情况更为严重。 、 和 分别是引起甲癣的三大类真菌中最常见的病原体。女性感染更为常见。NDMs是主要的病原体,趾甲是甲癣最常见的发病部位。
甲癣的病原体模式和临床症状因地理区域和年龄而异,因此对甲癣进行反复的流行病学调查似乎至关重要。