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希腊南部一家学术性指甲科三年内甲癣的流行病学情况

Epidemiology of Onychomycosis in an Academic Nail Unit in South Greece during a Three-Year Period.

作者信息

Gregoriou Stamatios, Mpali Nikoletta, Vrioni Georgia, Hatzidimitriou Eleni, Chryssou Stella-Eugenia, Rigopoulos Dimitrios

机构信息

National and Kapodistrian University of Athens 1st Department of Dermatology and Venereology, A. Sygros Hospital for Skin and Venereal Diseases, Athens, Greece.

Department of Microbiology, A. Sygros Hospital for Skin and Venereal Diseases, Athens, Greece.

出版信息

Skin Appendage Disord. 2020 Mar;6(2):102-107. doi: 10.1159/000504812. Epub 2019 Dec 19.

DOI:10.1159/000504812
PMID:32258053
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7109406/
Abstract

BACKGROUND

Onychomycosis is the most common disease of the nails.

OBJECTIVE

This retrospective study aimed at evaluating the epidemiology of onychomycosis in adult patients in South Greece during the 2015-2017 period.

MATERIAL AND METHODS

A total of 3,226 patients with clinical signs of possible onychomycosis were included. Diagnosis was confirmed by microscopy with KOH 20% and by culture in Sabouraud agar with and without actidione.

RESULTS

Diagnosis of onychomycosis was confirmed in 27.99% of the patients. Men were infected more often (40.04%) than women (23.30%). Toenails (68.77%) were infected more than fingernails (31.23%) in both sexes. Onychomycosis in fingernails was more common among women (39.74%) than men (18.51%). Men were more often diagnosed with onychomycosis in toenails (81.49%) than women (60.26%). Dermatophytes were the most frequently isolated fungi (34.11%), followed by (29.79%) and non-dermatophyte molds (NDM) (7.20%). In fingernails, the most frequently isolated fungus was spp. (84.04%), followed by dermatophytes (3.55%) and NDM (0.71%). In toenails, dermatophytes (47.99%) were more commonly identified, followed by NDM (10.14%) and spp. (5.15%).

CONCLUSION

Onychomycosis in Greece follows a pattern of higher incidence in males, with toenails more frequently infected with and fingernails more frequently infected with in the present era.

摘要

背景

甲癣是最常见的指甲疾病。

目的

这项回顾性研究旨在评估2015 - 2017年期间希腊南部成年患者甲癣的流行病学情况。

材料与方法

共纳入3226例有疑似甲癣临床症状的患者。通过20%氢氧化钾显微镜检查以及在含或不含放线菌酮的沙氏琼脂培养基上培养来确诊。

结果

27.99%的患者确诊为甲癣。男性感染率(40.04%)高于女性(23.30%)。男女两性中,趾甲感染率(68.77%)高于指甲(31.23%)。女性指甲甲癣(39.74%)比男性(18.51%)更常见。男性趾甲甲癣确诊率(81.49%)高于女性(60.26%)。皮肤癣菌是最常分离出的真菌(34.11%),其次是酵母菌(29.79%)和非皮肤癣菌霉菌(NDM)(7.20%)。在指甲中,最常分离出的真菌是念珠菌属(84.04%),其次是皮肤癣菌(3.55%)和NDM(0.71%)。在趾甲中,皮肤癣菌(47.99%)更常见,其次是NDM(10.14%)和念珠菌属(5.15%)。

结论

在当今时代,希腊的甲癣呈现男性发病率较高的模式,趾甲更常感染皮肤癣菌,而指甲更常感染念珠菌属。

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