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抗击疟疾:成果渐消,挑战日增。

The fight against malaria: Diminishing gains and growing challenges.

机构信息

Clinton Health Access Initiative, Boston, MA, USA.

Environmental Health and Ecological Science Department, Ifakara Health Institute, Ifakara, Tanzania.

出版信息

Sci Transl Med. 2022 Jun 29;14(651):eabn3256. doi: 10.1126/scitranslmed.abn3256.

Abstract

Since the year 2000, historic reductions in malaria incidence and mortality have been driven by the widespread distribution of bed nets, drugs, and insecticides for the prevention and treatment of malaria. Scale-up of these tools has been enabled by an increase in malaria financing compounded by price reductions, yet these trends are unlikely to continue at the same rate. Rapid population growth in high-endemic areas requires procurement of more of these tools just to maintain current coverage, even as prices are likely to increase as resistance to drugs and insecticides forces shifts to newer products. Further progress toward the long-term goal of malaria eradication requires a combination of greater funding, more cost-effective resource allocation, and fundamental changes to the global malaria control strategy.

摘要

自 2000 年以来,疟疾发病率和死亡率的历史性下降,主要得益于广泛分发预防和治疗疟疾的蚊帐、药品和杀虫剂。这些工具的推广得益于疟疾资金的增加,再加上价格的降低,但这些趋势不太可能以同样的速度持续下去。在高传播地区,人口的快速增长需要采购更多的这些工具,以维持当前的覆盖范围,即使随着对药物和杀虫剂的抗药性迫使转向更新的产品,价格可能会上涨。要实现消除疟疾这一长期目标,需要在更大的资金投入、更具成本效益的资源配置以及对全球疟疾控制战略进行根本变革方面取得进展。

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