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经皮穴位电神经刺激(Acu-TENS)联合瑜伽眼球运动治疗 2 型糖尿病伴原发性开角型青光眼患者短期眼压反应:一项随机对照试验。

Short-Term Intraocular Pressure Response to the Combined Effect of Transcutaneous Electrical Nerve Stimulation over Acupoint (Acu-TENS) and Yoga Ocular Exercise in Type 2 Diabetic Patients with Primary Open-Angle Glaucoma: A Randomized Controlled trial.

机构信息

Department of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University, Giza, Egypt.

Basic Science Department, Faculty of Physical Therapy, Cairo University, Giza, Egypt.

出版信息

J Acupunct Meridian Stud. 2021 Oct 31;14(5):193-199. doi: 10.51507/j.jams.2021.14.5.193.

Abstract

BACKGROUND

Despite the adherence to medications, the control of the modifiable key risk factor-intraocular pressure (IOP)-for the progression of primary open-angle glaucoma (POAG) in diabetics is usually difficult; hence, many glaucoma patients try other alternative therapeutic options. Objectives: This randomized controlled study investigated the short-term IOP response to the combined effects of transcutaneous electrical nerve stimulation over acupoint (Acu-TENS) and yoga ocular exercise in type 2 diabetics with POAG.

METHODS

Eighty diabetics with bilateral POAG, ages ≥ 50 years, IOP > 21 mmHg in both eyes, and a body mass index below 30 kg/m were included in this trial. The patients were randomly assigned to group A (n = 40; this group received 20 minutes of yoga ocular exercise followed by 20 minutes of active Acu-TENS over bilateral BL 61 and BL 62 acupoints) and group B (n = 40; this group received the same protocol as group A but with a placebo Acu-TENS). The repeated measurement of IOP were recorded before, immediately after, 30 minutes, and 60 minutes after the sessions.

RESULTS

The repeated measures analysis of variance revealed a greater significant decline of IOP in group A than group B in both eyes at the consecutive intervals of time measurements.

CONCLUSION

According to this short-term observation, the addition of Acu-TENS to yoga ocular exercise could reduce the high IOP in diabetic patients with POAG, but further longterm trials are needed.

摘要

背景

尽管患者坚持用药,但是对于糖尿病并发原发性开角型青光眼(POAG)患者,其主要可修正风险因素——眼内压(IOP)的控制通常较为困难;因此,许多青光眼患者会尝试其他替代治疗方案。目的:本随机对照研究旨在探究经皮穴位电刺激(Acu-TENS)联合瑜伽眼球运动对 2 型糖尿病并发 POAG 患者短期 IOP 的影响。

方法

本试验纳入了 80 例年龄≥50 岁、双眼 POAG、双眼 IOP>21mmHg 且身体质量指数(BMI)<30kg/m²的糖尿病患者。患者被随机分为 A 组(n=40;该组患者接受 20 分钟瑜伽眼球运动,随后在双侧 BL 61 和 BL 62 穴位进行 20 分钟主动 Acu-TENS)和 B 组(n=40;该组接受与 A 组相同的方案,但接受安慰剂 Acu-TENS)。在治疗前、治疗后即刻、治疗后 30 分钟和 60 分钟时,重复测量双眼的 IOP。

结果

重复测量方差分析显示,A 组双眼的 IOP 在各个时间点的连续测量中均显著低于 B 组。

结论

根据本次短期观察,瑜伽眼球运动联合 Acu-TENS 可降低糖尿病并发 POAG 患者的高 IOP,但仍需进行长期试验。

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