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经皮穴位电刺激对2型糖尿病患者的影响:一项随机对照试验

Effect of transcutaneous electrical nerve stimulation at acupoints on patients with type 2 diabetes mellitus: a randomized controlled trial.

作者信息

Zhiyuan Wu, Ming Yang, Jie Jia, Yi Wu, Tiansheng Huang, Mingfen Li, Zhijie He, Zhenzhen Guo, Pang Leung Mason Chin

出版信息

J Tradit Chin Med. 2015 Apr;35(2):134-40. doi: 10.1016/s0254-6272(15)30020-0.

DOI:10.1016/s0254-6272(15)30020-0
PMID:25975045
Abstract

OBJECTIVE

To examine whether transcutaneous electric nerve stimulation at acupoints (Acu-TENS) improved the biochemical and physical indices of patients with type 2 diabetes mellitus (T2DM).

METHODS

Ninety subjects with T2DM were divided randomly into a control group (n = 30), aerobic exercise group (n = 30), or Acu-TENS group (n = 30). In addition to conventional diabetes drug treatment, patients in the Acu-TENS group received acupoint stimulation, the aerobic exercise group engaged in walking exercises, and the control group was given sham electrical stimulation. All groups were treated for 30 min for each session and five times a week for 2 months. The indices of glycosylated hemoglobin, 2 h postprandial glucose, fasting serum insulin, triglyceride, total cholesterol, and body mass index were assessed at pre-treatment, post-treatment, and follow-up, which was 2 months after treatment.

RESULTS

The indices of the control group were not changed (P > 0.05) at the three time points. At the pre-treatment measurement, there were significant differences (P > 0.05) in indices among the three groups. At post-treatment, each index of the two groups was lower than that of the control group (P < 0.05), and improved in comparison with the pre-treatment measurement (P < 0.05). In follow-up, each index of the aerobic exercise group and Acu-TENS group increased, but was still decreased compared with the pre-treatment value (P < 0.05), excluding body mass index.

CONCLUSION

Acu-TENS could improve the state of patients with T2DM and be used as a therapy in clinical application.

摘要

目的

探讨经皮穴位电刺激(Acu-TENS)是否能改善2型糖尿病(T2DM)患者的生化和身体指标。

方法

将90例T2DM患者随机分为对照组(n = 30)、有氧运动组(n = 30)或Acu-TENS组(n = 30)。除常规糖尿病药物治疗外,Acu-TENS组患者接受穴位刺激,有氧运动组进行步行锻炼,对照组给予假电刺激。每组每次治疗30分钟,每周5次,共2个月。在治疗前、治疗后及治疗后2个月的随访时评估糖化血红蛋白、餐后2小时血糖、空腹血清胰岛素、甘油三酯、总胆固醇和体重指数等指标。

结果

对照组在三个时间点指标均无变化(P > 0.05)。在治疗前测量时,三组指标存在显著差异(P > 0.05)。治疗后,两组的各项指标均低于对照组(P < 0.05),且与治疗前测量值相比有所改善(P < 0.05)。随访时,有氧运动组和Acu-TENS组的各项指标均有所上升,但与治疗前值相比仍下降(P < 0.05),体重指数除外。

结论

Acu-TENS可改善T2DM患者的状态,可作为一种疗法应用于临床。

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