Bestwick Henry, Teh Jye Quan, Mowforth Oliver, Grodzinski Ben, Kotter Mark, Davies Benjamin
Clinical School, University of Cambridge, Cambridge, United Kingdom.
Academic Neurosurgery Unit, Department of Clinical Neurosurgery, University of Cambridge, Cambridge, United Kingdom.
Interact J Med Res. 2022 Jun 30;11(1):e36194. doi: 10.2196/36194.
Degenerative cervical myelopathy (DCM) is a common, disabling condition of symptomatic cervical spinal cord compression that requires significant research advances to improve patient outcomes. A James Lind Alliance Partnership recently identified the top research priorities for DCM. To effectively address these priorities, appropriate funding of DCM research is essential.
The aim of this paper is to review current funding in DCM research and highlight future research funding opportunities.
A systematic search of Web of Science for "cervical AND myelopathy" was conducted. Papers exclusively studying DCM with declared funding and published between January 1, 1995, and March 21, 2020, were considered eligible. Funding sources were classified by country of origin and organization type. A grant search was also conducted using Dimensions.ai (Digital Science Ltd).
A total of 621 papers were included, with 300 unique funding bodies. The top funders were AO Spine (n=87); National Institutes of Health, USA (n=63); and National Natural Science Foundation, China (n=63). Funding sources in the USA (n=242) supported the most DCM research, followed by China (n=209) and Japan (n=116). Funding in the USA was primarily provided by corporate or nonprofit organizations (146/242, 60.3%), while in China, the majority of funding was from institutions (208/209, 99.5%). Dimensions.ai gives an estimate for the total declared grant funding awards for DCM-specific research. Data here showed 180 grants awarded specifically for DCM research, with a total value of US $45.6 million since 1996.
DCM funding appears to be predominantly from the USA, China, and Japan, aligning with areas of high DCM research activity and underpinning the importance of funding to increasing research capacity. The existing funding sources differ from medical research in general, representing opportunities for future investment in DCM.
退行性颈椎脊髓病(DCM)是一种常见的、导致残疾的有症状的颈椎脊髓受压疾病,需要重大的研究进展来改善患者预后。詹姆斯·林德联盟合作组织最近确定了DCM的首要研究重点。为有效解决这些重点问题,对DCM研究进行适当的资金投入至关重要。
本文旨在回顾DCM研究的当前资金投入情况,并突出未来的研究资金机会。
在科学网中对“颈椎 AND 脊髓病”进行了系统检索。仅研究有明确资金支持且于1995年1月1日至2020年3月21日发表的DCM的论文被视为符合条件。资金来源按原产国和组织类型进行分类。还使用Dimensions.ai(数字科学有限公司)进行了资助搜索。
共纳入621篇论文,有300个不同的资助机构。主要资助者为AO脊柱(n = 87);美国国立卫生研究院(n = 63);以及中国国家自然科学基金(n = 63)。美国的资助来源(n = 242)支持的DCM研究最多,其次是中国(n = 209)和日本(n = 116)。美国的资金主要由企业或非营利组织提供(146/242,60.3%),而在中国,大部分资金来自机构(208/209,99.5%)。Dimensions.ai给出了针对DCM特定研究的申报资助总额的估计值。此处数据显示自1996年以来有180项专门授予DCM研究的资助,总价值为4560万美元。
DCM的资金似乎主要来自美国、中国和日本,这与DCM研究活跃的领域相符,并突出了资金对提高研究能力的重要性。现有的资金来源与一般医学研究不同,这代表了未来对DCM投资的机会。