儿童时期的心理健康与中年时期的心血管代谢风险：来自 1958 年英国出生队列的研究结果。
Psychological Well-Being in Childhood and Cardiometabolic Risk in Middle Adulthood: Findings From the 1958 British Birth Cohort.
机构信息
Department of Psychology, Chapman University.
Department of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health.
出版信息
Psychol Sci. 2022 Aug;33(8):1199-1211. doi: 10.1177/09567976221075608. Epub 2022 Jun 30.
Childhood adversity is linked to poor cardiometabolic outcomes, but less is known about positive childhood factors. Using data from 4,007 members of the 1958 British Birth Cohort, we investigated whether children with greater psychological well-being had lower adulthood cardiometabolic risk. At age 11, participants wrote essays about their future. Two judges rated each essay for nine psychological well-being items (Finn's = .82-.91), which were combined into a standardized overall score (Cronbach's α = .91). When participants reached age 45, nurses assessed their blood pressure, heart rate, lipids, glycosylated hemoglobin, fibrinogen, and C-reactive protein, which were standardized and summed for total cardiometabolic risk. Regressions indicated that children with greater psychological well-being had lower cardiometabolic risk ( = -0.14, 95% confidence interval [CI] = [-0.28, -0.006]): specifically, healthier total cholesterol ( = -0.04, 95% CI = [-0.07, -0.003]) and triglycerides ( = -0.06, 95% CI = [-0.09, -0.02]). Childhood psychological well-being may promote adulthood cardiometabolic health.
童年逆境与较差的心血代谢结局相关，但关于积极的童年因素知之甚少。本研究利用来自 1958 年英国出生队列的 4007 名成员的数据，调查了具有更好心理幸福感的儿童是否具有更低的成年心血代谢风险。在 11 岁时，参与者撰写了关于未来的文章。两位评审员根据九项心理幸福感项目对每篇文章进行评分（Finn's =.82-.91），将这些项目综合为标准化的总体得分（Cronbach's α =.91）。当参与者达到 45 岁时，护士评估了他们的血压、心率、血脂、糖化血红蛋白、纤维蛋白原和 C 反应蛋白，这些指标经过标准化并汇总为总心血代谢风险。回归分析表明，心理幸福感较高的儿童具有较低的心血代谢风险（ = -0.14，95%置信区间 [CI] = [-0.28，-0.006]）：具体来说，更健康的总胆固醇（ = -0.04，95% CI = [-0.07，-0.003]）和甘油三酯（ = -0.06，95% CI = [-0.09，-0.02]）。儿童期的心理幸福感可能促进成年后的心血代谢健康。
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