• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Masquelet-Ilizarov 技术治疗感染性胫骨骨不连清创后骨丢失。

Masquelet-Ilizarov technique for the management of bone loss post debridement of infected tibial nonunion.

机构信息

Department of Orthopedic Surgery, Faculty of Medicine, Tanta University, Tanta, Egypt.

出版信息

Int Orthop. 2022 Sep;46(9):1937-1944. doi: 10.1007/s00264-022-05494-y. Epub 2022 Jun 30.

DOI:10.1007/s00264-022-05494-y
PMID:35773530
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9372116/
Abstract

PURPOSE

Masquelet and Ilizarov techniques have their advantages and shortcomings in the reconstruction of bone defects. The aim of this study was to evaluate the effectiveness of the combination of both techniques for the management of infected tibial nonunion to combine the advantages of both techniques with avoidance of shortcomings of both of them.

PATIENTS AND METHODS

A prospective single-centre study was performed during the period from 2012 to 2019. Patients with the infected nonunion of the tibia with bone defect were included. Patients with pathological fractures or non-infected bone loss were excluded. Management protocol for all patients consisted of two stages. The first stage was Masquelet induced membrane technique and the second stage was Ilizarov bone transport. The results were assessed based on both objective (clinical and radiographic evaluation) and subjective criteria (limb function and patient satisfaction).

RESULTS

Thirty-two patients were included in this study. The mean size of the defect was 6 cm. Ilizarov bone transport was done through the induced membrane chamber in all cases with an average follow-up of 28 months. Successful reconstruction without recurrence of infection was achieved in 30 cases (94%). No other bone or soft tissue procedure was needed with satisfactory functional outcome in 27 out of 30 cases (90%). Three cases had unsatisfactory results due to leg length discrepancy, joint stiffness, and persistent pain.

CONCLUSIONS

Masquelet-Ilizarov technique can be used for the management of infected nonunion tibia with high satisfactory results without the need for complex soft tissue procedures.

摘要

目的

Masquelet 和 Ilizarov 技术在骨缺损重建中各有优缺点。本研究旨在评估两种技术联合应用于感染性胫骨骨不连的疗效,以结合两种技术的优点,避免两者的缺点。

方法

这是一项 2012 年至 2019 年期间进行的前瞻性单中心研究。纳入患有感染性胫骨骨不连伴骨缺损的患者。排除病理性骨折或无感染性骨丢失的患者。所有患者的治疗方案均分为两个阶段。第一阶段是 Masquelet 诱导膜技术,第二阶段是 Ilizarov 骨搬运。结果基于客观(临床和影像学评估)和主观标准(肢体功能和患者满意度)进行评估。

结果

本研究共纳入 32 例患者。缺损平均大小为 6cm。在所有病例中,均通过诱导膜室进行 Ilizarov 骨搬运,平均随访 28 个月。30 例(94%)成功重建,无感染复发。27 例(90%)患者功能结局满意,无需其他骨或软组织手术。3 例因肢体长度差异、关节僵硬和持续疼痛而结果不满意。

结论

Masquelet-Ilizarov 技术可用于治疗感染性胫骨骨不连,疗效满意,无需复杂的软组织手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9372116/75a4dd0ddf8b/264_2022_5494_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9372116/9c5717d6d115/264_2022_5494_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9372116/15d56963afab/264_2022_5494_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9372116/13d09ed5f453/264_2022_5494_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9372116/4a23a36a67cb/264_2022_5494_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9372116/75a4dd0ddf8b/264_2022_5494_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9372116/9c5717d6d115/264_2022_5494_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9372116/15d56963afab/264_2022_5494_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9372116/13d09ed5f453/264_2022_5494_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9372116/4a23a36a67cb/264_2022_5494_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9372116/75a4dd0ddf8b/264_2022_5494_Fig5_HTML.jpg

相似文献

1
Masquelet-Ilizarov technique for the management of bone loss post debridement of infected tibial nonunion.Masquelet-Ilizarov 技术治疗感染性胫骨骨不连清创后骨丢失。
Int Orthop. 2022 Sep;46(9):1937-1944. doi: 10.1007/s00264-022-05494-y. Epub 2022 Jun 30.
2
The treatment of infected tibial nonunion by bone transport using the Ilizarov external fixator and a systematic review of infected tibial nonunion treated by Ilizarov methods.采用伊利扎洛夫外固定器行骨搬运治疗感染性胫骨骨不连及对伊利扎洛夫方法治疗感染性胫骨骨不连的系统评价
Acta Orthop Belg. 2014 Sep;80(3):426-35.
3
Prospective randomized comparison of bone transport versus Masquelet technique in infected gap nonunion of tibia.胫骨感染性骨不连中骨搬运与Masquelet技术的前瞻性随机对照研究
Arch Orthop Trauma Surg. 2022 Aug;142(8):1923-1932. doi: 10.1007/s00402-021-03935-8. Epub 2021 May 13.
4
Masquelet technique versus Ilizarov bone transport for reconstruction of lower extremity bone defects following posttraumatic osteomyelitis.用于创伤后骨髓炎后下肢骨缺损重建的Masquelet技术与Ilizarov骨搬运技术对比
Injury. 2017 Jul;48(7):1616-1622. doi: 10.1016/j.injury.2017.03.042. Epub 2017 Apr 4.
5
Quality of life and complications at the different stages of bone transport for treatment infected nonunion of the tibia.胫骨感染性骨不连治疗中不同骨搬运阶段的生活质量及并发症
Medicine (Baltimore). 2017 Nov;96(45):e8569. doi: 10.1097/MD.0000000000008569.
6
Management of Chronic Infected Intra-Articular Fractures of the Proximal Tibia with Ilizarov Ring Fixation.采用伊里扎洛夫环形固定治疗胫骨近端慢性感染性关节内骨折
J Knee Surg. 2020 Feb;33(2):213-222. doi: 10.1055/s-0038-1677512. Epub 2019 Jan 16.
7
Infected tibial nonunion in children: Is radical debridement mandatory?儿童感染性胫骨骨不连:是否必须进行彻底清创?
Injury. 2019 Feb;50(2):590-597. doi: 10.1016/j.injury.2018.10.043. Epub 2018 Oct 29.
8
A treatment for large defects of the tibia caused by infected nonunion: Ilizarov method with bone segment extension.骨段延长的伊利扎罗夫法治疗感染性骨不连导致的胫骨大缺损
Ir J Med Sci. 2014 Sep;183(3):423-8. doi: 10.1007/s11845-013-1032-9. Epub 2013 Oct 29.
9
Ilizarov segmental bone transport of infected tibial nonunions requiring extensive debridement with an average distraction length of 9,5 centimetres. Is it safe?伊里扎洛夫节段性骨搬运治疗需要广泛清创的感染性胫骨骨不连,平均牵开长度为 9.5 厘米。它安全吗?
Injury. 2021 Aug;52(8):2425-2433. doi: 10.1016/j.injury.2019.12.025. Epub 2019 Dec 17.
10
The management of infected nonunion of tibia with a segmental defect using simultaneous fixation with a monorail fixator and a locked plate.采用单轨道固定器和锁定钢板同时固定治疗合并节段性骨缺损的感染性胫骨骨不连的处理方法。
Bone Joint J. 2018 Aug;100-B(8):1094-1099. doi: 10.1302/0301-620X.100B8.BJJ-2017-1442.R1.

引用本文的文献

1
The Use of Ossein-Hydroxyapatite Complex in Conjunction with the Ilizarov Method in the Treatment of Tibial Nonunion.骨胶原-羟基磷灰石复合物联合伊利扎洛夫方法治疗胫骨骨不连的应用
J Clin Med. 2025 May 12;14(10):3353. doi: 10.3390/jcm14103353.
2
[Effectiveness of three-dimensional-printed microporous titanium prostheses combined with flap implantation in treatment of large segmental infectious bone defects in limbs].三维打印微孔钛假体联合皮瓣植入治疗四肢大段感染性骨缺损的疗效
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2025 May 15;39(5):521-528. doi: 10.7507/1002-1892.202502045.
3
Bone marrow fluid enhances the osteogenic activity of induced membrane leading to spontaneous osteogenesis: experimental validation and application in tibiofibular fusion for support reconstruction of segmental tibial defects.

本文引用的文献

1
Ilizarov bone transport combined with the Masquelet technique for bone defects of various etiologies (preliminary results).伊利扎洛夫骨搬运联合马斯克莱技术治疗各种病因所致骨缺损(初步结果)
World J Orthop. 2022 Mar 18;13(3):278-288. doi: 10.5312/wjo.v13.i3.278.
2
Traumatic Composite Bone and Soft Tissue Loss of the Leg: Region-Specific Classification and Treatment Algorithm.腿部创伤性复合骨和软组织损失:区域特异性分类和治疗算法。
Injury. 2020 Jun;51(6):1352-1361. doi: 10.1016/j.injury.2020.03.041. Epub 2020 Apr 18.
3
Masquelet technique versus Ilizarov bone transport for reconstruction of lower extremity bone defects following posttraumatic osteomyelitis.
骨髓液增强诱导膜的成骨活性导致自发骨生成:实验验证及其在胫腓骨融合中用于支持节段性胫骨缺损重建的应用
J Transl Med. 2025 Feb 27;23(1):239. doi: 10.1186/s12967-024-05840-1.
4
Chimeric Free Flaps Based on End-to-Side Anastomosis for Complex Lower Extremity Reconstruction.基于端侧吻合的嵌合游离皮瓣用于复杂下肢重建
Ann Plast Surg. 2025 Feb 1;94(2):185-191. doi: 10.1097/SAP.0000000000004180. Epub 2024 Dec 26.
5
Local muscle or myocutaneous flap transfer for emergent repair of Gustilo IIIB open tibiofibular fractures.局部肌肉或肌皮瓣转移用于急诊修复 Gustilo IIIB 型开放性胫腓骨骨折。
Sci Rep. 2024 Oct 27;14(1):25609. doi: 10.1038/s41598-024-77429-z.
6
Masquelet Technique Combined with Ilizarov External Fixator, Reamer-irrigator-aspirator, and Flap Transplantation in an Open Tibial Fracture: A Case Report.Masquelet技术联合Ilizarov外固定架、扩髓-冲洗-吸引装置及皮瓣移植治疗开放性胫骨骨折:1例病例报告
J Orthop Case Rep. 2024 Sep;14(9):65-69. doi: 10.13107/jocr.2024.v14.i09.4732.
7
Open segmental tibial bone defects treated with Ilizarov frame: a radiological and functional outcome study with average ten year follow-up.采用伊利扎洛夫外固定架治疗节段性胫骨骨缺损:平均十年随访的放射学和功能结果研究。
Int Orthop. 2024 Oct;48(10):2519-2523. doi: 10.1007/s00264-024-06277-3. Epub 2024 Aug 29.
8
Applying 3D-printed prostheses to reconstruct critical-sized bone defects of tibial diaphysis (> 10 cm) caused by osteomyelitis and aseptic non-union.应用 3D 打印假体重建由骨髓炎和无菌性骨不连引起的胫骨骨干临界尺寸 (> 10 cm) 骨缺损。
J Orthop Surg Res. 2024 Jul 20;19(1):418. doi: 10.1186/s13018-024-04926-2.
9
Which surgical technique may yield the best results in large, infected, segmental non-unions of the tibial shaft? A scoping review.哪种手术技术可能在胫骨大段感染性骨不连中获得最佳效果?系统评价。
Eur J Trauma Emerg Surg. 2024 Aug;50(4):1537-1545. doi: 10.1007/s00068-024-02478-y. Epub 2024 Mar 6.
10
A novel primary antibiotic cement-coated locking plate as a temporary fixation for the treatment of open tibial fracture.新型原发性抗生素涂层锁定钢板作为治疗开放性胫骨骨折的临时固定。
Sci Rep. 2023 Dec 11;13(1):21890. doi: 10.1038/s41598-023-49460-z.
用于创伤后骨髓炎后下肢骨缺损重建的Masquelet技术与Ilizarov骨搬运技术对比
Injury. 2017 Jul;48(7):1616-1622. doi: 10.1016/j.injury.2017.03.042. Epub 2017 Apr 4.
4
Restoration of long bone defects treated with the induced membrane technique: protocol and outcomes.采用诱导膜技术治疗长骨缺损的修复:方案与结果
Injury. 2016 Dec;47 Suppl 6:S53-S61. doi: 10.1016/S0020-1383(16)30840-3.
5
Ilizarov bone transport combined with antibiotic cement spacer for infected tibial nonunion.伊利扎洛夫骨搬运联合抗生素骨水泥间隔物治疗感染性胫骨骨不连
Int J Clin Exp Med. 2015 Jun 15;8(6):10058-65. eCollection 2015.
6
The treatment of infected tibial nonunion by bone transport using the Ilizarov external fixator and a systematic review of infected tibial nonunion treated by Ilizarov methods.采用伊利扎洛夫外固定器行骨搬运治疗感染性胫骨骨不连及对伊利扎洛夫方法治疗感染性胫骨骨不连的系统评价
Acta Orthop Belg. 2014 Sep;80(3):426-35.
7
Bone transport through an induced membrane in the management of tibial bone defects resulting from chronic osteomyelitis.通过诱导膜进行骨搬运治疗慢性骨髓炎所致胫骨骨缺损
Strategies Trauma Limb Reconstr. 2015 Apr;10(1):27-33. doi: 10.1007/s11751-015-0221-7. Epub 2015 Apr 4.
8
Difficulties and challenges to diagnose and treat post-traumatic long bone osteomyelitis.创伤后长骨骨髓炎诊断与治疗的困难和挑战。
Eur J Orthop Surg Traumatol. 2015 Jan;25(1):1-3. doi: 10.1007/s00590-014-1576-z. Epub 2014 Dec 6.
9
Bone transport using the Ilizarov method: a review of complications in 100 consecutive cases.采用伊里扎洛夫方法进行骨搬运:100例连续病例并发症的回顾
Strategies Trauma Limb Reconstr. 2010 Apr;5(1):17-22. doi: 10.1007/s11751-010-0085-9. Epub 2010 Mar 9.
10
Acute shortening and re-lengthening in the management of bone and soft-tissue loss in complicated fractures of the tibia.急性缩短与再延长在复杂胫骨骨折骨与软组织缺损治疗中的应用
J Bone Joint Surg Br. 2007 Jan;89(1):80-8. doi: 10.1302/0301-620X.89B1.17595.