Characterization of Clinical Trains in Huzhou, China.

BACKGROUND

subspecies causes salmonellosis in humans and animals and is an important antecedent of food infections worldwide. This study collected 105 clinical . isolates from diarrhoea samples from six sentinel hospitals for active surveillance of foodborne diseases in Huzhou, China, between 2018 and 2020. These represented all the isolates collected in Huzhou during that period.

METHODS

The isolates were characterized by serovar determination, antimicrobial susceptibility tests, and pulse-field gel electrophoresis (PFGE) typing.

RESULTS

The 105 strains were mainly . (35.24%, 95% CI from 25.95 to 44.53%) and . (18.10%, 95% CI from 10.61 to 25.58%). Testing indicated that the resistance rate of the strains ranged from 0.00% to 70.48%, and the highest resistance rate was for ampicillin (70.48%; 74/105), followed by tetracycline (67.62%; 71/105) and doxycycline (65.71%; 69/105). Following I digestion, the 105 strains yielded 93 PFGE patterns, and 15 clones had similarity values >85.00%.

CONCLUSIONS

Our analyses revealed the serovar distribution of isolates recovered from diarrhoea patients and the characteristics of resistant strains in Huzhou from 2018 to 2020. Our results highlight a serovar shift and a concerning number of multidrug-resistant (MDR) strains. Continued surveillance of and their MDR profiles and efforts to control the rapid increase in antimicrobial resistance among in Huzhou are needed.