Department of General Surgery, Trakya University Faculty of Medicine, Edirne-Türkiye.
Department of Radiology, Trakya University Faculty of Medicine, Edirne-Türkiye.
Ulus Travma Acil Cerrahi Derg. 2022 Jul;28(7):940-946. doi: 10.14744/tjtes.2022.90249.
The aims of this study were to investigate the clinical significance of systemic inflammatory response index (SIRI), systemic inflammation index (SII), prognostic nutritional index (PNI), and Glasgow prognostic score (GPS) in deciding whether to perform cholecystostomy when determining if cholecystostomy is the right choice for acute cholecystitis (AC) patients.
Between January 2018 and December 2020, 126 consecutive patients with AC with and without cholecystostomy were retrospectively recruited from the Trakya University in Edirne, Turkey. Group I included AC patients with cholecystostomy and Group II included AC patients without cholecystostomy. The neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and lymphocyte/monocyte ratio (LMR) were calculated. The PNI and SII were calculated RESULTS: There is significant difference between the two groups by the comparison of SIRI, SII, PNI, and GPS values (p<0.001). In Group I, SIRI, SII, and GPS values are higher than the Group II and PNI value in Group I is lower than the Group II. Furthermore, the NLR and PLR ratios in Group I are significantly higher than Group II, and the LMR ratio in Group I is significantly lower than Group II.
According to our study, we can say that NLR, PLR, SII, SIRI, and GPS are positive predictors and LMR and PNI are negative predictors for the severity of AC. Therefore, when we decide to treat AC medically, we may prefer the application of chole-cystostomy tube at the beginning of hospitalization by the help of evaluating NLR, PLR, LMR, SIRI, SII, GPS, and PNI values.
本研究旨在探讨全身炎症反应指数（SIRI）、全身炎症指数（SII）、预后营养指数（PNI）和格拉斯哥预后评分（GPS）在决定是否行胆囊造口术时对急性胆囊炎（AC）患者的临床意义。
本研究回顾性纳入了 2018 年 1 月至 2020 年 12 月期间土耳其埃迪尔内的特克亚大学收治的 126 例接受和未接受胆囊造口术的 AC 连续患者。组 I 包括接受胆囊造口术的 AC 患者，组 II 包括未接受胆囊造口术的 AC 患者。计算中性粒细胞/淋巴细胞比值（NLR）、血小板/淋巴细胞比值（PLR）和淋巴细胞/单核细胞比值（LMR）。计算 PNI 和 SII。
通过比较 SIRI、SII、PNI 和 GPS 值，两组之间存在显著差异（p<0.001）。在组 I 中，SIRI、SII 和 GPS 值高于组 II，而组 I 的 PNI 值低于组 II。此外，组 I 的 NLR 和 PLR 比值明显高于组 II，组 I 的 LMR 比值明显低于组 II。
根据我们的研究，我们可以说 NLR、PLR、SII、SIRI 和 GPS 是 AC 严重程度的正预测因子，而 LMR 和 PNI 是负预测因子。因此，当我们决定对 AC 进行药物治疗时，我们可以通过评估 NLR、PLR、LMR、SIRI、SII、GPS 和 PNI 值，在住院初期更倾向于应用胆囊造口术。
