National Center for Trauma & Emergency Medicine Research, The Gertner Institute for Epidemiology & Health Policy Research, Sheba Medical Center, Tel-HaShomer, Israel; Department of Emergency & Disaster Management, School of Public Health, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv-Yafo, Israel.
Health Technology Assessment and Policy Unit, The Gertner Institute for Epidemiology & Health Policy Research, Sheba Medical Center, Tel-HaShomer, Israel.
Public Health. 2022 Aug;209:19-22. doi: 10.1016/j.puhe.2022.05.018. Epub 2022 Jun 1.
The challenge of waning immunity and reinfection has been an acknowledged concern since the beginning of the COVID-19 pandemic. In the ongoing outbreak, reinfection rates are increasing alongside breakthrough cases among vaccinated individuals. The objective of this study was to examine the demographic characteristics associated with vaccination uptake among individuals previously infected with COVID-19 and to evaluate the period elapsed between the last vaccine dose and infection.
A retrospective-archive study was conducted.
Data were extracted from the Israeli Ministry of Health's open COVID-19 database.
The study found that uptake of vaccination in previously infected individuals is relatively low. When examining gender, previously infected females were more likely to receive vaccination than previously infected males. Similarly, differences in vaccination uptake exist between age groups. When examining the interval between the last vaccine dose and infection, the most significant breakthrough infection rate was observed among individuals aged 20-59 years.
This study shows that there are specific populations subgroups that may serve as reservoirs of viral spread. Individuals in these groups may experience a false sense of security from a perceived sense of acquired long-term immunity, resulting in low levels of vaccine uptake and non-compliance with protective behaviours. Targeted messaging should be used to reemphasise the need for continued protective behaviours.
自 COVID-19 大流行开始以来,免疫力下降和再次感染的挑战一直是人们公认的关注点。在持续爆发的疫情中,接种疫苗人群中的再次感染率和突破病例都在增加。本研究的目的是研究与以前感染过 COVID-19 的个体接种疫苗相关的人口统计学特征,并评估最后一次疫苗接种和感染之间的时间间隔。
回顾性档案研究。
从以色列卫生部的公开 COVID-19 数据库中提取数据。
研究发现,以前感染过的个体接种疫苗的比例相对较低。在检查性别时,以前感染过的女性比以前感染过的男性更有可能接种疫苗。同样,不同年龄组的疫苗接种率存在差异。在检查最后一次疫苗接种和感染之间的间隔时,发现 20-59 岁人群的突破性感染率最高。
本研究表明,存在特定的人群亚组,可能成为病毒传播的储库。这些群体中的个体可能会因获得长期免疫的错觉而产生安全感,从而导致疫苗接种率低和不遵守保护行为。应使用有针对性的信息来再次强调继续采取保护行为的必要性。