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中国脊髓损伤的流行病学:对中英文文献的系统评价

Epidemiology of spinal cord injury in China: A systematic review of the chinese and english literature.

作者信息

Chen Chuandong, Qiao Xu, Liu Wei, Fekete Christine, Reinhardt Jan D

机构信息

Institute for Disaster Management and Reconstruction, Sichuan University, Sichuan, Chengdu, China.

West China School of Public Health and West China Fourth Hospital, Sichuan University, Sichuan, Chengdu, China.

出版信息

Spinal Cord. 2022 Dec;60(12):1050-1061. doi: 10.1038/s41393-022-00826-6. Epub 2022 Jul 1.

Abstract

STUDY DESIGN

Systematic review.

OBJECTIVES

We aimed to provide a comprehensive overview of the English and Chinese literature reporting epidemiological data on spinal cord injury (SCI) in China.

METHODS

3 English and 3 Chinese language electronic databases were searched from the earliest record to 15 March 2020. Sociodemographic characteristics, incidence rates, etiology and lesion characteristics, in-hospital mortality, and secondary health conditions and complications were extracted from included reports.

RESULTS

A total of 51 studies were included, 32 in the Chinese language. Forty-seven studies were based on hospital records. Mean age of incident cases ranged from 34 to 55 years and male-to-female ratios ranged from 0.35:1 to 15.3:1. SCI incidence varied from 14.6 to 60.6 per million. Thirty-five studies reported only on traumatic SCI with traffic accidents, high falls, low falls and being hit by objects being the most common causes. Specific causes for non-traumatic SCI were poorly reported. Proportions with tetraplegia and complete injury ranged from 37.4% to 82.0% and 14.1% to 73.9%, respectively. Reported in-hospital mortality attributed to SCI varied from 1.1% to 18.4%. Leading cause of in-hospital mortality for acute SCI was respiratory problems; respiratory problems, urinary tract infections and pressure sores were the most common complications.

CONCLUSION

Epidemiological data on SCI in China are only available for a limited number of provinces and mostly outdated. Updated data on incidence with accurate geographical information and etiology across all Chinese provinces are needed for targeted implementation of preventive strategies. Research on community outcomes needs to be developed in China.

摘要

研究设计

系统评价。

目的

我们旨在全面概述报告中国脊髓损伤(SCI)流行病学数据的英文和中文文献。

方法

检索了3个英文和3个中文电子数据库,检索时间从最早记录至2020年3月15日。从纳入的报告中提取社会人口学特征、发病率、病因和损伤特征、住院死亡率以及继发性健康状况和并发症。

结果

共纳入51项研究,其中32项为中文研究。47项研究基于医院记录。发病病例的平均年龄在34至55岁之间,男女比例在0.35:1至15.3:1之间。SCI发病率从每百万14.6至60.6不等。35项研究仅报告了创伤性SCI,交通事故、高处坠落、低处坠落和被物体撞击是最常见的原因。非创伤性SCI的具体病因报告较少。四肢瘫痪和完全损伤的比例分别在37.4%至82.0%和14.1%至73.9%之间。报告的因SCI导致的住院死亡率在1.1%至18.4%之间。急性SCI住院死亡的主要原因是呼吸问题;呼吸问题、尿路感染和压疮是最常见的并发症。

结论

中国SCI的流行病学数据仅适用于少数省份,且大多过时。需要更新所有中国省份发病率的准确地理信息和病因数据,以便有针对性地实施预防策略。中国需要开展社区结局研究。

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