Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Firenze, Italy.
SOD Malattie Infettive e Tropicali, Azienda Ospedaliero Universitaria Careggi, Firenze, Italy.
Trans R Soc Trop Med Hyg. 2023 Jan 3;117(1):58-60. doi: 10.1093/trstmh/trac065.
Chagas disease represents a major public health concern in several Latin American countries, including Bolivia.
We present a longitudinal serosurvey for Trypanosoma cruzi antibodies among a cohort of 120 school-age children from rural communities in the Bolivian Chaco at three time points between 2017 and 2019. Serum samples extracted from dry blood spots collected on filter paper were tested for T. cruzi antibodies by enzyme-linked immunosorbent assay and rapid diagnostic test.
T. cruzi antibodies were detected in 7/120 (5.8%), 8/120 (6.7%) and 11/120 (9.2%) samples in 2017, 2018 and 2019, respectively. An average incidence of 1.76 per 100 person-years was observed.
Our findings support the persistence of vector-borne T. cruzi transmission in this area, highlighting the need for strengthening multidisciplinary efforts against Chagas disease.
恰加斯病是拉丁美洲多个国家(包括玻利维亚)的一个主要公共卫生关注点。
我们在 2017 年至 2019 年期间的三个时间点,对玻利维亚查科地区农村社区的 120 名学龄儿童进行了纵向血清学调查,以检测克氏锥虫抗体。从滤纸采集的干血斑中提取血清样本,通过酶联免疫吸附试验和快速诊断检测来检测 T. cruzi 抗体。
2017 年、2018 年和 2019 年分别有 7/120(5.8%)、8/120(6.7%)和 11/120(9.2%)的样本中检测到 T. cruzi 抗体。平均发病率为每 100 人年 1.76 例。
我们的研究结果支持该地区媒介传播的 T. cruzi 持续存在,强调了需要加强多学科努力以对抗恰加斯病。